ID   H0E4E9_9ACTN            Unreviewed;       327 AA.
AC   H0E4E9;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   SubName: Full=Quinone oxidoreductase {ECO:0000313|EMBL:EHN11447.1};
DE            EC=1.6.5.5 {ECO:0000313|EMBL:EHN11447.1};
GN   ORFNames=PAI11_16800 {ECO:0000313|EMBL:EHN11447.1};
OS   Patulibacter medicamentivorans.
OC   Bacteria; Actinomycetota; Thermoleophilia; Solirubrobacterales;
OC   Patulibacteraceae; Patulibacter.
OX   NCBI_TaxID=1097667 {ECO:0000313|EMBL:EHN11447.1, ECO:0000313|Proteomes:UP000005143};
RN   [1] {ECO:0000313|EMBL:EHN11447.1, ECO:0000313|Proteomes:UP000005143}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=I11 {ECO:0000313|EMBL:EHN11447.1,
RC   ECO:0000313|Proteomes:UP000005143};
RX   PubMed=23212173; DOI=10.1007/s10532-012-9610-5;
RA   Almeida B., Kjeldal H., Lolas I., Knudsen A.D., Carvalho G., Nielsen K.L.,
RA   Barreto Crespo M.T., Stensballe A., Nielsen J.L.;
RT   "Quantitative proteomic analysis of ibuprofen-degrading Patulibacter sp.
RT   strain I11.";
RL   Biodegradation 24:615-630(2013).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EHN11447.1}.
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DR   EMBL; AGUD01000104; EHN11447.1; -; Genomic_DNA.
DR   RefSeq; WP_007573250.1; NZ_AGUD01000104.1.
DR   AlphaFoldDB; H0E4E9; -.
DR   OrthoDB; 4190732at2; -.
DR   Proteomes; UP000005143; Unassembled WGS sequence.
DR   GO; GO:0003960; F:NADPH:quinone reductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd08241; QOR1; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   InterPro; IPR002364; Quin_OxRdtase/zeta-crystal_CS.
DR   PANTHER; PTHR43677:SF3; PROSTAGLANDIN REDUCTASE 3; 1.
DR   PANTHER; PTHR43677; SHORT-CHAIN DEHYDROGENASE/REDUCTASE; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS01162; QOR_ZETA_CRYSTAL; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000313|EMBL:EHN11447.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005143}.
FT   DOMAIN          11..325
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   327 AA;  34030 MW;  0115F705CC5F9E3F CRC64;
     MRAQQITELT GPDTALKLVD LPEPGPADNL LGGEGVVVEV GAAGVSFPEL LQTRGMYQMK
     PPVPFVPGSE VGGVVRSAPA GSGLEPGQRV AAFCMLGGWS EVAVASPDLT FPIPDRLDDA
     QGAALILNYH TAWFALVTRG RLKEGESVLV HGAAGGVGTA TLQVAKGLGA RTFAVVSTDE
     KERIARAAGA DEVVRSDGPW KDQVKELSGG GVDLIIDPVG GDRFTDSLRS LRPAGRLAVV
     GFTGGEIPSV KVNRLLLGNT EVLGAAWGEW LFRDRTLGPA IGAEIGKLID AGAIDPPIGA
     RFPLERAVDA LKTLDERRAV GKVVLEP
//