ID H0E6J6_9ACTN Unreviewed; 264 AA.
AC H0E6J6;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Ketoreductase {ECO:0000313|EMBL:EHN10695.1};
GN ORFNames=PAI11_24460 {ECO:0000313|EMBL:EHN10695.1};
OS Patulibacter medicamentivorans.
OC Bacteria; Actinomycetota; Thermoleophilia; Solirubrobacterales;
OC Patulibacteraceae; Patulibacter.
OX NCBI_TaxID=1097667 {ECO:0000313|EMBL:EHN10695.1, ECO:0000313|Proteomes:UP000005143};
RN [1] {ECO:0000313|EMBL:EHN10695.1, ECO:0000313|Proteomes:UP000005143}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=I11 {ECO:0000313|EMBL:EHN10695.1,
RC ECO:0000313|Proteomes:UP000005143};
RX PubMed=23212173; DOI=10.1007/s10532-012-9610-5;
RA Almeida B., Kjeldal H., Lolas I., Knudsen A.D., Carvalho G., Nielsen K.L.,
RA Barreto Crespo M.T., Stensballe A., Nielsen J.L.;
RT "Quantitative proteomic analysis of ibuprofen-degrading Patulibacter sp.
RT strain I11.";
RL Biodegradation 24:615-630(2013).
CC -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC family. {ECO:0000256|ARBA:ARBA00006484}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHN10695.1}.
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DR EMBL; AGUD01000205; EHN10695.1; -; Genomic_DNA.
DR RefSeq; WP_007575417.1; NZ_AGUD01000205.1.
DR AlphaFoldDB; H0E6J6; -.
DR PATRIC; fig|1097667.3.peg.2427; -.
DR OrthoDB; 5242555at2; -.
DR Proteomes; UP000005143; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd05233; SDR_c; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR002347; SDR_fam.
DR PANTHER; PTHR43975; ZGC:101858; 1.
DR PANTHER; PTHR43975:SF2; ZGC:101858; 1.
DR Pfam; PF13561; adh_short_C2; 1.
DR PRINTS; PR00081; GDHRDH.
DR SMART; SM00822; PKS_KR; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000005143}.
SQ SEQUENCE 264 AA; 27239 MW; AC781FA3834FA0C4 CRC64;
MDLELTGETI VVTGATSGIG AAVTRRLAEE GAHVLLVARD EQRLRAAVAG LPGGPHAFAA
VDVGDLDAGE RIVAAALAEL GRLDAVVMAA GASRRARPEE LTEADWEQQW RLNVLAPQRL
LLAASDALVS APRGGRAVLV SSSSGKRPSP GNMAYGVTKS AQLALSRAWA DHLAPRGVRV
NAVAPGPIDG EMWLQPGGLA DQAAAAAGVT REQALESARA RVPLRRFGTP DEIADAIVLL
ASHRAGFTAG AAWSVDGGSV PFYL
//
