ID H0EK59_GLAL7 Unreviewed; 2254 AA.
AC H0EK59;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Putative Hydroxamate-type ferrichrome siderophore peptide synthetase {ECO:0000313|EMBL:EHL01089.1};
GN ORFNames=M7I_2950 {ECO:0000313|EMBL:EHL01089.1};
OS Glarea lozoyensis (strain ATCC 74030 / MF5533).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Helotiaceae; Glarea.
OX NCBI_TaxID=1104152 {ECO:0000313|EMBL:EHL01089.1, ECO:0000313|Proteomes:UP000005446};
RN [1] {ECO:0000313|EMBL:EHL01089.1, ECO:0000313|Proteomes:UP000005446}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 74030 / MF5533 {ECO:0000313|Proteomes:UP000005446};
RX PubMed=22302591; DOI=10.1128/EC.05302-11;
RA Youssar L., Gruening B.A., Erxleben A., Guenther S., Huettel W.;
RT "Genome sequence of the fungus Glarea lozoyensis: the first genome sequence
RT of a species from the Helotiaceae family.";
RL Eukaryot. Cell 11:250-250(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHL01089.1}.
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DR EMBL; AGUE01000061; EHL01089.1; -; Genomic_DNA.
DR HOGENOM; CLU_000092_0_0_1; -.
DR InParanoid; H0EK59; -.
DR Proteomes; UP000005446; Unassembled WGS sequence.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR CDD; cd05918; A_NRPS_SidN3_like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 2.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 3.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 4.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR PANTHER; PTHR45527:SF7; HYDROXAMATE-TYPE FERRICHROME SIDEROPHORE PEPTIDE SYNTHETASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 2.
DR Pfam; PF00668; Condensation; 3.
DR Pfam; PF00550; PP-binding; 3.
DR SMART; SM00823; PKS_PP; 2.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47336; ACP-like; 3.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 7.
DR PROSITE; PS50075; CARRIER; 3.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000005446}.
FT DOMAIN 666..743
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 1211..1284
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 1772..1845
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 2254 AA; 250116 MW; AD9E5001D5646039 CRC64;
MSKTKQVVST YDFDTFDRSH RGGICEKHKM SSEDIEAIRP CTAIQRGMVA QSIHSSGGDN
QDAASKKEFW KKEENKIIVN KFPDLTPLHV SETTSAVQEI SSRKSTSELE GLCKESGVTM
QAAGQAAWAR LLAAYVGETS TTFGMTLSGR SIHEDADQLL ARTMESNAQL HKHQFTPLTS
IQKWAGYPEG KIFDTLFAYQ KVTASEGETE VPWKVIKEQA SNPQSACDVA ATSHFGIDLL
SVTPPKEYEL SSEITLLHQF LERGTRQWPD KTAFEFATSL DPDNLRTKSW SYSQVEQEAN
KIANLLLQEG AQPGDIIAIY FDKCPEASFA IVGIMKAGCA YVALDPNAPI DRVKFILRDS
GAKIVLTAGK PAQLLVESLE EKVIKLDQPN TFKKQSTPKG CLITHENAVQ AMLSFQRLFA
GHWNSESKWL QFASFHFDVS VLEQFWSWSV GICVASAPRD LIFEDIPGTI RQLGITHIDL
TPSLARLLHP DDVPSLWKGV FITGGEQLRQ EILDVWGDKG CIYNGYGPTE ATIGVTMYPR
VPRNGKPSNI GSQFDNVGSF VLKPGTTIPV LRGGIGELCV SGKLVGKGYL NRPDLTNERF
PILTEFDERV YRTGDLVRIL HDGTFIFLGR ADDQVKLRGQ RLELSEINEV IKKAVSDLSD
VVTDTQDWNK AENKIVEIIA GAMNVDMASV TRNSSIFELG QDSISIIGFA RALQNAGLEN
VKLSTVKNHP NIGALVAALS GSGSVDRGQE SAYMEAKQRI AAFSQKHMVA VCQELDVEAA
SVEAVAPCTP VQEGMIFRFL ENEGALYFNK FAFRVEESID LEVLASAWRR VVRGAQVLRT
RFVATDDGFA QIVVKESAFE WAEKVVDYTA MEKMEALKQP YSIALENDEH GGVMTIQMFH
GLYDGISLNL LLERVVDEFR STSNLDYGPR FQHSLPYGPL AKVEGAKPFW TEQLKDWSPK
SLPLASDSQQ DISAKLSVDQ LSGFENLRTS LSVTPQAVLQ AAWLSVLQTL IPDPTIGLVT
SGRTIDFDNA ENIIGPLFNT VPFHCPVSQA RTFTDLIHKC HDFNMKMQDF QHTPLKDIQK
WSPAQPGSPI FESLFVFQRG GDDGFAEGIW QEIEDEDVVA DYPLAFEATM SLDGRSLGLV
IVAQGGVISQ GKAEELLGGV EETLRRIVDS GGDAVIDNNQ AAEKSAPGTT LITSLRSRTT
KGDVRNDFQW TDKATFIRME IAQLAKVSVD SIHEHSSIFE LGLDSIDVIK LSSRLKKRGI
ELPVSVIIRC QNIAQMSLKL SSAPSKPREN SLTVLKDLSQ KLEAYLRKSG KLPEGTETVL
PATPLQQSMV NEMIRSGYER YFNIDVLRIQ EDVDVVKLIA AVTKAVENSP ILSTRFVEVE
DPELPVSYAQ VIPKEKRFTP YRVDLGKSHY EDFDDLLATL KVDCTRKAIE NGELFQVQFI
NDSTAKYFVM AAAHALYDGS SMRLLHDDIK TAYHDKLSSR PSFMPFLEEA VRSTTEEAKK
FWRTTLSDIP HASLPTKDPP PKATTVHRLD RRSKVPFKAI EDLSKSSRVT LQSMAQTTYS
LVLAHLTKQL EVLFGSVISC RDTEEANSVQ FPLMNTVAVR SILHGTLSDM LTHIQNLSDM
TRQYQHFPLG TAQAYALASR SHDGDDKSTR LFDSLFIYQG RRETAGETLY ESVQGNREVE
FPMCVEMEVV DGEIVWTIAC KSDFCDERDT KAILDALDVV LERLVEDKEA QTIVSTGDGV
SICGLPPFRT QSVQTKKSIS QDPTEQRDTA WSQVEVKIRG ALHELSGVPE DAIRQDLTIF
HLGLDSILVL KLPALFRKSG IKLSVSDILR EQTVQAMAKL AESKNFQDEV AVDVDQIIGD
AVERVKFESG GAKLEELRES GAAEDVMPVT AGQLHMIRQW QASRGRLFYP TFSYQISGTL
DKVALEQAWG KLCDRHAILR TGFIEVGDSV LQVVFKDPDN PVQYEESSVS HDLINPPLTL
TIQNNNNKPL MKLRIHHALY DGISLPILLD DLHSLYVNIN HAFPQPTSNF KQFIAQTLTS
SSTTQEKWQS YLSSAPPKTR TKARHSNRTE IYHPSLPISS LKPRARELGI SIDALLLASV
AKKYAHHAHT AENLILGIYL ANRAPFGEDL SSLAAPTLNL LPLLINDPLG RSVGDLAREI
QHDVTRISNK DMIGASLDEI YNWTGVKVEG FVNIVKSPAQ IPTESKPVWE SIDENGDGAG
EVEVRTDEKF PDVDESKVEA YPVSSSYNEI LVEV
//
