ID H0IXR1_9GAMM Unreviewed; 532 AA.
AC H0IXR1;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=diguanylate cyclase {ECO:0000256|ARBA:ARBA00012528};
DE EC=2.7.7.65 {ECO:0000256|ARBA:ARBA00012528};
GN ORFNames=MOY_00735 {ECO:0000313|EMBL:EHK62534.1};
OS Halomonas sp. GFAJ-1.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Halomonadaceae; Halomonas.
OX NCBI_TaxID=1118153 {ECO:0000313|EMBL:EHK62534.1, ECO:0000313|Proteomes:UP000004512};
RN [1] {ECO:0000313|EMBL:EHK62534.1, ECO:0000313|Proteomes:UP000004512}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GFAJ-1 {ECO:0000313|EMBL:EHK62534.1,
RC ECO:0000313|Proteomes:UP000004512};
RX PubMed=22408239; DOI=10.1128/JB.06664-11;
RA Phung le T., Silver S., Trimble W.L., Gilbert J.A.;
RT "Draft Genome of Halomonas Species Strain GFAJ-1 (ATCC BAA-2256).";
RL J. Bacteriol. 194:1835-1836(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHK62534.1}.
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DR EMBL; AHBC01000002; EHK62534.1; -; Genomic_DNA.
DR RefSeq; WP_009095415.1; NZ_CP016490.1.
DR AlphaFoldDB; H0IXR1; -.
DR STRING; 1118153.MOY_00735; -.
DR KEGG; hag:BB497_12005; -.
DR PATRIC; fig|1118153.6.peg.144; -.
DR eggNOG; COG3706; Bacteria.
DR OrthoDB; 9812260at2; -.
DR Proteomes; UP000004512; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd06225; HAMP; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR InterPro; IPR007892; CHASE4.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR Pfam; PF05228; CHASE4; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000004512};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 272..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 382..518
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 532 AA; 59770 MW; 4DB62D57F406B264 CRC64;
MNPRTPRSLR FRFFAALSGL LIGAITALAA ISIWLIFPAL QEEERATIKR ELDRVERSFQ
LDQQQLHAQV RDWAHWDDTY QFVQGNYPRY ADVNFSQEMF ENMRYQLMAF FTRNGDVHFL
AGINPATGSY QTCHTPADIC SWMAPWVNSM QAAIKENRTD QTNIYPDNPL AAVASSPILL
TDKSGISPGW LFKTRTLNNE WLRFLEDYTG LSINLSVSNQ AAPLNDTFSF SGNTVVAERY
LPISGSTAPA SLAVGVELDR TSYLTSLATF RYVLLWTAGL MIAVIVIVLL LLEKIVLKPL
RLLTQFTQQV GTQEINHDKL TNRNDEIGLL ARTFEQQFTR QRQLNEKLSI LSTHDPLTGL
PNRRLFDQEL QRAVEQAIAH HTPVAVMMLD IDHFKLFNDH YGHPKGDHCL ATVGATLQAF
AENNDVLIAR TGGEEFSVLA EMPADQAHRL ANAINAEIDA LNYPHNFSPV APHLTFSIGI
SALEINEHFT PTALMSTADQ ALYEAKKAGR HQVRLYAPPL VKETISTHNT PP
//
