ID H0J3L0_9GAMM Unreviewed; 351 AA.
AC H0J3L0;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Efflux transporter, RND family, MFP subunit {ECO:0000313|EMBL:EHK60547.1};
GN ORFNames=MOY_11110 {ECO:0000313|EMBL:EHK60547.1};
OS Halomonas sp. GFAJ-1.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Halomonadaceae; Halomonas.
OX NCBI_TaxID=1118153 {ECO:0000313|EMBL:EHK60547.1, ECO:0000313|Proteomes:UP000004512};
RN [1] {ECO:0000313|EMBL:EHK60547.1, ECO:0000313|Proteomes:UP000004512}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GFAJ-1 {ECO:0000313|EMBL:EHK60547.1,
RC ECO:0000313|Proteomes:UP000004512};
RX PubMed=22408239; DOI=10.1128/JB.06664-11;
RA Phung le T., Silver S., Trimble W.L., Gilbert J.A.;
RT "Draft Genome of Halomonas Species Strain GFAJ-1 (ATCC BAA-2256).";
RL J. Bacteriol. 194:1835-1836(2012).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHK60547.1}.
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DR EMBL; AHBC01000039; EHK60547.1; -; Genomic_DNA.
DR RefSeq; WP_009099689.1; NZ_CP016490.1.
DR AlphaFoldDB; H0J3L0; -.
DR STRING; 1118153.MOY_11110; -.
DR KEGG; hag:BB497_14230; -.
DR PATRIC; fig|1118153.6.peg.2261; -.
DR eggNOG; COG0845; Bacteria.
DR OrthoDB; 1185083at2; -.
DR Proteomes; UP000004512; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469:SF20; LIPOPROTEIN-RELATED; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000004512}.
FT DOMAIN 55..222
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT COILED 98..156
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 351 AA; 38186 MW; DB11753CA833E626 CRC64;
MRPNVLWIVL IAAVLLVGCS NDEAPPEPPV QVIKLLETDQ QDFFPSRRFI GRVEAKSTVN
LAFRVGGRIE TFPAVQGTTI PRGELIAQLD PTDYALQVRS AEAEVEQARK HLNRQRNLYS
HNAVSETVLD AARADAELAE TQLENAKQQL AYTTLNAPFD ALVTRRLVEN HTTVPPNAEV
VRIQDISELR VRINVPEALM QHLESGSAFN IEAEIATLPG ERIPLVYREH VTEPDVVAQT
YQVEFAPADG VSPIALPGTT ATVIIELEEA LTTSVVAVPS SALDHTEEGV FRVWVYDPET
GTVSPQQVVV GEVTNDLVII VAGLAPGVPI AATGVQLLRD GMRVKPLEAA L
//
