ID H0J4H3_9GAMM Unreviewed; 636 AA.
AC H0J4H3;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE SubName: Full=Inosine-5-monophpsphate dehydrogenase {ECO:0000313|EMBL:EHK60168.1};
GN ORFNames=MOY_12689 {ECO:0000313|EMBL:EHK60168.1};
OS Halomonas sp. GFAJ-1.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Halomonadaceae; Halomonas.
OX NCBI_TaxID=1118153 {ECO:0000313|EMBL:EHK60168.1, ECO:0000313|Proteomes:UP000004512};
RN [1] {ECO:0000313|EMBL:EHK60168.1, ECO:0000313|Proteomes:UP000004512}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GFAJ-1 {ECO:0000313|EMBL:EHK60168.1,
RC ECO:0000313|Proteomes:UP000004512};
RX PubMed=22408239; DOI=10.1128/JB.06664-11;
RA Phung le T., Silver S., Trimble W.L., Gilbert J.A.;
RT "Draft Genome of Halomonas Species Strain GFAJ-1 (ATCC BAA-2256).";
RL J. Bacteriol. 194:1835-1836(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHK60168.1}.
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DR EMBL; AHBC01000043; EHK60168.1; -; Genomic_DNA.
DR RefSeq; WP_009100349.1; NZ_CP016490.1.
DR AlphaFoldDB; H0J4H3; -.
DR STRING; 1118153.MOY_12689; -.
DR KEGG; hag:BB497_16145; -.
DR PATRIC; fig|1118153.6.peg.2580; -.
DR eggNOG; COG2905; Bacteria.
DR OrthoDB; 9808528at2; -.
DR Proteomes; UP000004512; Unassembled WGS sequence.
DR GO; GO:0008773; F:[protein-PII] uridylyltransferase activity; IEA:InterPro.
DR CDD; cd00038; CAP_ED; 1.
DR CDD; cd04587; CBS_pair_CAP-ED_NT_Pol-beta-like_DUF294_assoc; 1.
DR CDD; cd05401; NT_GlnE_GlnD_like; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR018821; DUF294_put_nucleoTrafse_sb-bd.
DR InterPro; IPR005105; GlnD_Uridyltrans_N.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR43080; CBS DOMAIN-CONTAINING PROTEIN CBSX3, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43080:SF2; CBS DOMAIN-CONTAINING PROTEIN CBSX3, MITOCHONDRIAL; 1.
DR Pfam; PF00571; CBS; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR Pfam; PF03445; DUF294; 1.
DR Pfam; PF10335; DUF294_C; 1.
DR SMART; SM00116; CBS; 2.
DR SMART; SM00100; cNMP; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR PROSITE; PS51371; CBS; 2.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Reference proteome {ECO:0000313|Proteomes:UP000004512}.
FT DOMAIN 17..115
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT DOMAIN 155..228
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 235..291
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 636 AA; 71635 MW; C067028C7E5C9296 CRC64;
MEVELLEIRQ HMGQFPPFDG LSDKLLDSIA AEVEVRYFKT GSEILKLDQS LTELCYIRSG
AVEVYRRQGE LYNRLGEGDI FGHFSLLRNH KVRLPATAIE DTLIYFISGA VFKRLCEEDD
NFADFVELER PRLETAAEQQ KKSNDMMVSR IRKLVSRYPV MVPSTTSVQE AAKQIGAAQA
SAVLVIDEGS GHPRYSFQDS EGKTWQMCGI LTDSDFRTRV VAEGLSPQTP IGDVVSERLI
TIQSDASIYE AMLTMLRSNV HHLPVLYRQR PVGVVHLSDI IRYETHSGLY LVSNIFNQSS
AQGLAKLLPD VRAAFVRMVQ EGANSQMVGS ALSTIGRSFT RRLLELAEEA LGPPPVPYCY
MVNGSMARNE QSIVTDQDNA LILSDDFNPT EHDAYFHALA AFVSDGLDAC GYTYCKGDVM
ATNRQWRQPL SVWKSYFKEW MANPTPEKLL HSSIFFDLDS IYGEDHFVEA LQDLIAETAP
QSPLFLAAMA RNALNRTPPL GFFRTFVMEK DGKHNNSINL KRRGTAPMVD LVRVHALACG
SKAQNSFKRL EDISHTQLLA TGVSDKLSYA LEFLCMSRIR HQVIDLQEDR APDNNIEPEN
VEDSERHTLK DAFQVLSNAQ KFLKFRYPVP AQRQGR
//
