ID H0PX52_9RHOO Unreviewed; 484 AA.
AC H0PX52;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Zn-dependent peptidase {ECO:0000313|EMBL:BAL23044.1};
GN ORFNames=AZKH_0704 {ECO:0000313|EMBL:BAL23044.1};
OS Azoarcus sp. KH32C.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales; Zoogloeaceae;
OC Azoarcus.
OX NCBI_TaxID=748247 {ECO:0000313|EMBL:BAL23044.1, ECO:0000313|Proteomes:UP000007106};
RN [1] {ECO:0000313|EMBL:BAL23044.1, ECO:0000313|Proteomes:UP000007106}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KH32C {ECO:0000313|EMBL:BAL23044.1,
RC ECO:0000313|Proteomes:UP000007106};
RA Nishizawa T., Tago T., Oshima K., Hattori M., Ishii S., Otsuka S.,
RA Senoo K.;
RT "Complete genome sequence of Azoarcus sp. KH32C.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase M16 family.
CC {ECO:0000256|ARBA:ARBA00007261, ECO:0000256|RuleBase:RU004447}.
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DR EMBL; AP012304; BAL23044.1; -; Genomic_DNA.
DR AlphaFoldDB; H0PX52; -.
DR STRING; 748247.AZKH_0704; -.
DR MEROPS; M16.019; -.
DR KEGG; aza:AZKH_0704; -.
DR PATRIC; fig|748247.4.peg.707; -.
DR eggNOG; COG0612; Bacteria.
DR HOGENOM; CLU_009902_1_0_4; -.
DR Proteomes; UP000007106; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 2.
DR InterPro; IPR011249; Metalloenz_LuxS/M16.
DR InterPro; IPR011765; Pept_M16_N.
DR InterPro; IPR001431; Pept_M16_Zn_BS.
DR InterPro; IPR007863; Peptidase_M16_C.
DR PANTHER; PTHR43690; NARDILYSIN; 1.
DR PANTHER; PTHR43690:SF17; PROTEIN YHJJ; 1.
DR Pfam; PF00675; Peptidase_M16; 1.
DR Pfam; PF05193; Peptidase_M16_C; 1.
DR SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 2.
DR PROSITE; PS00143; INSULINASE; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000007106};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 65..210
FT /note="Peptidase M16 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00675"
FT DOMAIN 221..400
FT /note="Peptidase M16 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05193"
SQ SEQUENCE 484 AA; 54261 MW; 4F952A76CEC7322E CRC64;
MRLHVERGAP EKQAVASREF YQMQDISMFR HIFPRTTMLA AALALAAGPL HANPFETTLP
NGMKVIVKED RRAPSVVHMV WYGAGSMDEA AGVSGVAHIL EHMMFKGTDK VGPGEFNKRV
AAIGGRDNAF TGQDYTAYFQ QVPSSRLGDV MALEADRMAH LKITDKEFKP ELEVVKEERR
LRTDDEPRSL VNEQLMATAF EAHPYHRPVI GWMTDLDTTG AEDARRWYRT WYVPNNARLV
VVGDVDHRQV FEMARKHYGP AKARPLPERR ITTEPEQQGM RSVVVRAPAE LPYLELAWKA
PTMRDPEQDR DVYALKVLAA VLDGYEGARL NRRLVRENRV AVSAGAGYDG SGRGPQLFTL
DGSPAPGKTV ADLETALRAE IKRIQDEGIA EDELRRVKTQ TVAGQVYKRD SLMGQAMEIG
FLESTGLSWR DDDKLLEGVR RVTAEEVQAV ARKYFSDDTL TRAQLDPLPI ADAKPHAHKP
GMRH
//
