ID H0Q2F8_9RHOO Unreviewed; 894 AA.
AC H0Q2F8;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor {ECO:0008006|Google:ProtNLM};
GN ORFNames=AZKH_4544 {ECO:0000313|EMBL:BAL26817.1};
OS Azoarcus sp. KH32C.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales; Zoogloeaceae;
OC Azoarcus.
OX NCBI_TaxID=748247 {ECO:0000313|EMBL:BAL26817.1, ECO:0000313|Proteomes:UP000007106};
RN [1] {ECO:0000313|EMBL:BAL26817.1, ECO:0000313|Proteomes:UP000007106}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KH32C {ECO:0000313|EMBL:BAL26817.1,
RC ECO:0000313|Proteomes:UP000007106};
RA Nishizawa T., Tago T., Oshima K., Hattori M., Ishii S., Otsuka S.,
RA Senoo K.;
RT "Complete genome sequence of Azoarcus sp. KH32C.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AP012304; BAL26817.1; -; Genomic_DNA.
DR RefSeq; WP_015438117.1; NC_020516.1.
DR AlphaFoldDB; H0Q2F8; -.
DR STRING; 748247.AZKH_4544; -.
DR KEGG; aza:AZKH_4544; -.
DR PATRIC; fig|748247.4.peg.4504; -.
DR eggNOG; COG3290; Bacteria.
DR eggNOG; COG5001; Bacteria.
DR HOGENOM; CLU_000445_70_20_4; -.
DR Proteomes; UP000007106; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR012226; Diguanyl_cyclase/Pdiesterase.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF2; BIOFILM ARCHITECTURE MAINTENANCE PROTEIN MBAA; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF12860; PAS_7; 2.
DR Pfam; PF13426; PAS_9; 1.
DR PIRSF; PIRSF005925; Dos; 3.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 3.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007106};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 40..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 339..383
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 410..463
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 495..628
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 637..891
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
FT COILED 623..650
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 894 AA; 98340 MW; A48CFEAA9B7D69DC CRC64;
MRHKGFVRSL LTRTAALGVL CIGMTLPAWG GETASPEGLS AGAALGLLVV GAGIGAVATS
FAGRRRARSD DGATQGALAE VERQSAYLHA VLNQLPQGIS VFDEHLRLRY WNQGLAEVLD
LPPELLRPGV GFDELLMVPA LRGEYGPGDP AELVRARREL ALRFEPHRFE RARPNGRTHL
VDGEPLFIGG KVAGFITTYT DITERRRTEE AQERQTRLLQ TIIDNIPGGV SLIDGNLQLM
ACNEELKRLL DFPPELFANG LPPLETLFRF NAQRGEYGPG DPDQIVAELL ERARHPVAHG
FERRRRDGTV LFVQGRPLPD GGFVTIYTDI SARKRDEERL QLADKVFENS PEAIVITDLS
QRILSVNPAY TAITGVAAQE AQGMLFRPEE SDSLGGSIAV WSVVNAHGAW QGETRGQRRD
GNYYPRSLTI TGVRDPATRQ LTHFIAMFSD ITERKRAEAD IQQLAYQDTL TGLANRFSLS
ARLQQSVADA RRNGQQLAVV FLDLDRFKHI NDSLGHAVGD ELLRQVALRL RGAVREVDTV
ARLGGDEFVV VLQSINGAND AAHVAAKLLK QLSAPYVVQG TELHTTPSIG LSLFPDDSSC
PDALMRNADT AMYHAKAAGR ARFQFYTEEM NQAATERLDL ERKLRGALKR GEFELWYQPQ
FASADGRLTG MEALIRWRHG EDGLIPPVRF IPIAEETGII LDIGNWVLGE ACRQARAWLD
EGLPPLRMSV NLSVRQLRDA TIVDTVKHAL ADSGLDPSLL ELEITESSVM ERPGEAIALL
QHLKDLGLQL AIDDFGTGHS SLSYLKLFPL DHLKIDRSFV SDIEHDANDA MIVAAAVSLA
HNLGLTVIAE GVETPVQIER LRELGCDELQ GYLFSKPLPV AEAGAYIREH NALV
//
