ID H0QIF0_ARTGO Unreviewed; 670 AA.
AC H0QIF0;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Phosphoenolpyruvate synthase {ECO:0000256|ARBA:ARBA00021623};
DE EC=2.7.9.2 {ECO:0000256|ARBA:ARBA00011996};
DE AltName: Full=Pyruvate, water dikinase {ECO:0000256|ARBA:ARBA00033470};
GN ORFNames=ARGLB_020_00210 {ECO:0000313|EMBL:GAB12601.1};
OS Arthrobacter globiformis NBRC 12137.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Arthrobacter.
OX NCBI_TaxID=1077972 {ECO:0000313|EMBL:GAB12601.1, ECO:0000313|Proteomes:UP000003828};
RN [1] {ECO:0000313|EMBL:GAB12601.1, ECO:0000313|Proteomes:UP000003828}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 12137 {ECO:0000313|EMBL:GAB12601.1,
RC ECO:0000313|Proteomes:UP000003828};
RA Miyazawa S., Hosoyama A., Tsuchikane K., Katsumata H., Yamazaki S.,
RA Fujita N.;
RT "Whole genome shotgun sequence of Arthrobacter globiformis NBRC 12137.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Catalyzes the phosphorylation of pyruvate to
CC phosphoenolpyruvate. {ECO:0000256|ARBA:ARBA00002988}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O + pyruvate = AMP + 2 H(+) + phosphate +
CC phosphoenolpyruvate; Xref=Rhea:RHEA:11364, ChEBI:CHEBI:15361,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58702, ChEBI:CHEBI:456215; EC=2.7.9.2;
CC Evidence={ECO:0000256|ARBA:ARBA00001518};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- PATHWAY: Carbohydrate biosynthesis; gluconeogenesis.
CC {ECO:0000256|ARBA:ARBA00004742}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAB12601.1}.
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DR EMBL; BAEG01000020; GAB12601.1; -; Genomic_DNA.
DR AlphaFoldDB; H0QIF0; -.
DR STRING; 1077972.ARGLB_020_00210; -.
DR eggNOG; COG0574; Bacteria.
DR Proteomes; UP000003828; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008986; F:pyruvate, water dikinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0006090; P:pyruvate metabolic process; IEA:InterPro.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR006319; PEP_synth.
DR InterPro; IPR002192; PPDK_AMP/ATP-bd.
DR PANTHER; PTHR43030; PHOSPHOENOLPYRUVATE SYNTHASE; 1.
DR PANTHER; PTHR43030:SF1; PHOSPHOENOLPYRUVATE SYNTHASE; 1.
DR Pfam; PF01326; PPDK_N; 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000003828};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 19..304
FT /note="Pyruvate phosphate dikinase AMP/ATP-binding"
FT /evidence="ECO:0000259|Pfam:PF01326"
SQ SEQUENCE 670 AA; 71896 MW; D88E58D0C59733D6 CRC64;
MTRKTTGPLT DFDRTDLAAA GGKGAALGEL VRQGFPVPGG FVITTDAYRW LLADTGLGAA
LDGMNQNVPD GGALRALFAR FGMPAALRAE IGEAYAALGG GAVAVRSSAT AEDLPGAAFA
GQQDSFLNVV GEEAVAKAVA DCWASLWTDR AIAYRRRQGI DPREVAIAVV VQKMVPADAA
GVMFTANPVT GERSETVVDA SPGLGEAVVS GRVTPEHYVL DRTGGIHSFR PGGGEVVVSP
DAGGGTRERP GVRSSVPTLA AAQLRELADL GRRAQEHFGR PQDIEWALAG GRIHVLQSRP
MTALPPQPLR LNAIQRRVGP FFIEMFQERP YPLDVSGWME QGILAMLHRM AGSVGVRFPS
VGELLPEEDG VVVQLVPPVP RLTLRALAAP LTLARRARQF KMAEWKDDFR FIHFLDRVDR
LNALDPEPLR WAEVVGVTRE SFATMRGITD LRSSYLPGMF LPMLRLRLLL VLLGRMRLAS
ALIAGAETRT SQANRSLEQL AAMVGADPGL AGAFASSDGP ALLQLVERDP AHAAFREAFA
GFLREYGNRE TVSVVLSSSP TWSDAPEVVL GLVKALLGQR PRTADQTGAA LAELKRHPLL
RFRRIRRHVL AAVDAARAGM AFREDSHFYA TKVIRPCAAR TGSLAGASLP TVSLMTPGTS
TTCGLRNWRQ
//
