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Database: UniProt
Entry: H0QQV8_ARTGO
LinkDB: H0QQV8_ARTGO
Original site: H0QQV8_ARTGO 
ID   H0QQV8_ARTGO            Unreviewed;       322 AA.
AC   H0QQV8;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   08-MAY-2019, entry version 32.
DE   SubName: Full=Putative 3-hydroxyacyl-CoA dehydrogenase {ECO:0000313|EMBL:GAB15209.1};
GN   ORFNames=ARGLB_083_00980 {ECO:0000313|EMBL:GAB15209.1};
OS   Arthrobacter globiformis NBRC 12137.
OC   Bacteria; Actinobacteria; Micrococcales; Micrococcaceae; Arthrobacter.
OX   NCBI_TaxID=1077972 {ECO:0000313|EMBL:GAB15209.1, ECO:0000313|Proteomes:UP000003828};
RN   [1] {ECO:0000313|EMBL:GAB15209.1, ECO:0000313|Proteomes:UP000003828}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 12137 {ECO:0000313|EMBL:GAB15209.1,
RC   ECO:0000313|Proteomes:UP000003828};
RA   Miyazawa S., Hosoyama A., Tsuchikane K., Katsumata H., Yamazaki S.,
RA   Fujita N.;
RT   "Whole genome shotgun sequence of Arthrobacter globiformis NBRC
RT   12137.";
RL   Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:GAB15209.1}.
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DR   EMBL; BAEG01000083; GAB15209.1; -; Genomic_DNA.
DR   RefSeq; WP_003804523.1; NZ_BAEG01000083.1.
DR   STRING; 1077972.ARGLB_083_00980; -.
DR   EnsemblBacteria; GAB15209; GAB15209; ARGLB_083_00980.
DR   OrthoDB; 862072at2; -.
DR   Proteomes; UP000003828; Unassembled WGS sequence.
DR   GO; GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:InterPro.
DR   Gene3D; 1.10.1040.10; -; 1.
DR   InterPro; IPR022694; 3-OHacyl-CoA_DH.
DR   InterPro; IPR006180; 3-OHacyl-CoA_DH_CS.
DR   InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR   InterPro; IPR006108; 3HC_DH_C.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF00725; 3HCDH; 1.
DR   Pfam; PF02737; 3HCDH_N; 1.
DR   PIRSF; PIRSF000105; HCDH; 1.
DR   SUPFAM; SSF48179; SSF48179; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   PROSITE; PS00067; 3HCDH; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000003828};
KW   NAD {ECO:0000256|PIRSR:PIRSR000105-2};
KW   Oxidoreductase {ECO:0000256|SAAS:SAAS00324627};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003828}.
FT   DOMAIN       11    190       3HCDH_N. {ECO:0000259|Pfam:PF02737}.
FT   DOMAIN      192    288       3HCDH. {ECO:0000259|Pfam:PF00725}.
FT   NP_BIND      15     20       NAD. {ECO:0000256|PIRSR:PIRSR000105-2}.
FT   BINDING      38     38       NAD. {ECO:0000256|PIRSR:PIRSR000105-2}.
FT   BINDING      98     98       NAD. {ECO:0000256|PIRSR:PIRSR000105-2}.
FT   BINDING     103    103       NAD. {ECO:0000256|PIRSR:PIRSR000105-2}.
FT   BINDING     125    125       NAD. {ECO:0000256|PIRSR:PIRSR000105-2}.
FT   BINDING     149    149       NAD. {ECO:0000256|PIRSR:PIRSR000105-2}.
FT   BINDING     282    282       NAD. {ECO:0000256|PIRSR:PIRSR000105-2}.
FT   SITE        146    146       Important for catalytic activity.
FT                                {ECO:0000256|PIRSR:PIRSR000105-1}.
SQ   SEQUENCE   322 AA;  34542 MW;  407B0B87B676F0E9 CRC64;
     MTDTPTSSRK FAVVGSGYMG GGIAQVLALG GARVALADVS AEVAQKNYER LLTESDQFVA
     DGLFPEGSTE ILKQNLWAAK DIEEAVADAD FIEEAVPEVI GIKHETLARI SAAARPDAVI
     GSNTSTISIA ELSQPVANPE RFLGVHFSNP SPFIPGVEII PHEGTSTETV AAVRDLVHSA
     NKQTAVVKDV TGFVLNRLQY ALFHEAAQLV EQGIATAEDV DTLVRTTFGF RLPFFGPFAI
     ADMAGLDVYN FCYKSLQTDF PERFATPKIL TDLVEAGKLG TKTGAGFLNV PAERTPELIA
     YRNKAYVAMQ KLIEELGPAP IN
//
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