ID H0TGN0_9BRAD Unreviewed; 516 AA.
AC H0TGN0;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Gamma-aminobutyrate metabolism dehydratase/isomerase {ECO:0000313|EMBL:CCE05618.1};
DE EC=4.2.1.- {ECO:0000313|EMBL:CCE05618.1};
DE EC=5.3.3.3 {ECO:0000313|EMBL:CCE05618.1};
GN ORFNames=BRAS3843_140037 {ECO:0000313|EMBL:CCE05618.1};
OS Bradyrhizobium sp. STM 3843.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Nitrobacteraceae; Bradyrhizobium.
OX NCBI_TaxID=551947 {ECO:0000313|EMBL:CCE05618.1, ECO:0000313|Proteomes:UP000002686};
RN [1] {ECO:0000313|Proteomes:UP000002686}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=STM3843 {ECO:0000313|Proteomes:UP000002686};
RX PubMed=24704842; DOI=10.3390/genes3010035;
RA Mornico D., Miche L., Bena G., Nouwen N., Vermeglio A., Vallenet D.,
RA Smith A.A., Giraud E., Medigue C., Moulin L.;
RT "Comparative genomics of aeschynomene symbionts: insights into the
RT ecological lifestyle of nod-independent photosynthetic bradyrhizobia.";
RL Genes (Basel) 3:35-61(2011).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCE05618.1}.
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DR EMBL; CAFK01000046; CCE05618.1; -; Genomic_DNA.
DR AlphaFoldDB; H0TGN0; -.
DR OrthoDB; 7233724at2; -.
DR Proteomes; UP000002686; Unassembled WGS sequence.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR GO; GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
DR GO; GO:0050393; F:vinylacetyl-CoA delta-isomerase activity; IEA:UniProtKB-EC.
DR Gene3D; 1.10.3140.10; 4-hydroxybutyryl-coa dehydratase, domain 1; 1.
DR Gene3D; 2.40.110.10; Butyryl-CoA Dehydrogenase, subunit A, domain 2; 1.
DR Gene3D; 1.20.140.10; Butyryl-CoA Dehydrogenase, subunit A, domain 3; 1.
DR InterPro; IPR046373; Acyl-CoA_Oxase/DH_mid-dom_sf.
DR InterPro; IPR036250; AcylCo_DH-like_C.
DR InterPro; IPR009100; AcylCoA_DH/oxidase_NM_dom_sf.
DR InterPro; IPR004925; HpaB/PvcC/4-BUDH.
DR InterPro; IPR024719; HpaB/PvcC/4-BUDH_C.
DR InterPro; IPR024674; HpaB/PvcC/4-BUDH_N.
DR PANTHER; PTHR36117; 4-HYDROXYPHENYLACETATE 3-MONOOXYGENASE-RELATED; 1.
DR PANTHER; PTHR36117:SF3; 4-HYDROXYPHENYLACETATE 3-MONOOXYGENASE-RELATED; 1.
DR Pfam; PF03241; HpaB; 1.
DR Pfam; PF11794; HpaB_N; 1.
DR PIRSF; PIRSF000331; HpaA_HpaB; 1.
DR SUPFAM; SSF47203; Acyl-CoA dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF56645; Acyl-CoA dehydrogenase NM domain-like; 1.
PE 4: Predicted;
KW FAD {ECO:0000256|PIRSR:PIRSR000331-2};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Isomerase {ECO:0000313|EMBL:CCE05618.1};
KW Lyase {ECO:0000313|EMBL:CCE05618.1};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000002686}.
FT DOMAIN 5..267
FT /note="HpaB/PvcC/4-BUDH N-terminal"
FT /evidence="ECO:0000259|Pfam:PF11794"
FT DOMAIN 278..474
FT /note="HpaB/PvcC/4-BUDH C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03241"
FT BINDING 189
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000331-2"
SQ SEQUENCE 516 AA; 56152 MW; 02617661BD4EEC4D CRC64;
MLMSGADYRE SLRAYKPRVF VNGNAVESVA DEPLLAPGVA GVGVTYDFAL KQEHVPIMTA
RQSTSGKIIN RMLHINETSQ DLLFKLEAVR LVCKTVGCAQ RYLTHDALNG IFQSTKLTDD
RHGTDYGQRF LAYLHDIQER DLTLGVAMTD AKGDRSKRPS AQVNPDVYVH IKERRPDGIV
IRGTKAIVTG APYMHEFLVM PCRTHNPEDK DFAVCCAVPC DAPGVTIISR PAGRPGEASA
KFSARYGQSV GVVMFDDVFV PHDRVFLSGE TEEGGFLTTS YATHHRHSCI GARAGFGDLL
IGAGALMIEA NGLDIERHAH IREAMVELIT ITESFYACGV ASSVYCTKDP AGSVMPDAVF
SNIGKLLLAT KIYDMHRVAH YVSGGLIVAL PGPEEDHNPE TKASLAAVMG GRPDIPADKR
AEVARFIEDL TVSHEAGWYS VISLHGGGSP EAMKREIWRN YPVVEKIELV EGLLDRSILE
DGRRVSKQPG RCCVTGCQVP EPPQKATLPA LEGAAE
//
