ID   H0TYU8_9BRAD            Unreviewed;       765 AA.
AC   H0TYU8;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   SubName: Full=Putative diguanylate cyclase (GGDEF)/phosphodiesterase (EAL) {ECO:0000313|EMBL:CCE11636.1};
GN   ORFNames=BRAS3843_740046 {ECO:0000313|EMBL:CCE11636.1};
OS   Bradyrhizobium sp. STM 3843.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Nitrobacteraceae; Bradyrhizobium.
OX   NCBI_TaxID=551947 {ECO:0000313|EMBL:CCE11636.1, ECO:0000313|Proteomes:UP000002686};
RN   [1] {ECO:0000313|Proteomes:UP000002686}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=STM3843 {ECO:0000313|Proteomes:UP000002686};
RX   PubMed=24704842; DOI=10.3390/genes3010035;
RA   Mornico D., Miche L., Bena G., Nouwen N., Vermeglio A., Vallenet D.,
RA   Smith A.A., Giraud E., Medigue C., Moulin L.;
RT   "Comparative genomics of aeschynomene symbionts: insights into the
RT   ecological lifestyle of nod-independent photosynthetic bradyrhizobia.";
RL   Genes (Basel) 3:35-61(2011).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCE11636.1}.
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DR   EMBL; CAFK01000323; CCE11636.1; -; Genomic_DNA.
DR   AlphaFoldDB; H0TYU8; -.
DR   Proteomes; UP000002686; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   PANTHER; PTHR44757:SF2; BIOFILM ARCHITECTURE MAINTENANCE PROTEIN MBAA; 1.
DR   PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF12860; PAS_7; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002686};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        42..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        87..105
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        111..129
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        136..154
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          356..488
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          497..747
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
SQ   SEQUENCE   765 AA;  84522 MW;  6058A23021B96CB9 CRC64;
     MSPAIHAALI DSLFQDPGPM FAGALCAAVA AVMTAIKSGD PKLWPCAVLL IIVGAFRSLD
     MRRYRRLRDT HQLSQSAIAR WELRYQVGAM VYALVLGVWC FAAVADSPDP VVHLIAIAVT
     LCYMSAGAGR TYGRPWIFHV QIVLACGPLT IALMLNGSPY YLGMAAFCVL FFLSLKHIST
     NLQKMFVTAF VAREGEAALA SQFDTALNNM PHGLCMFGAD GKLAVMNYRF CQMAGLPDDI
     IHSGASAHDI VGACVNAGSI SAVNGTIILA QIENTKAHNI VTTDPDLRRN RSLSWTFQPM
     AGGGAVVLLE DITERRQAEA RITHLARYDE LTTLPNRVSF RDEIERLLNI RQPDGQLSAL
     LFVDLDQFKQ VNDTLGHPCG DQLLCAVARR LRDMLRPEDF VARFGGDEFV VFQRNIRSND
     DAAILARRIV DHLSERYKID NHLVEIGASV GIAMTAPGVS ADTLLKNADM ALYRAKADGR
     GTFCFFRDEL AQTVEARRTL ELDLRKALAN EEFELFYQPL VNLKSGRIST CEALLRWNHP
     VRGTVSPVDI IPVAEDMGLI VDLGRWILRR ACLECVKWPE TVSVAVNFSP QQFHQRDVLS
     EVRYALEVSG LPPHRLEIEI TESSLLRNTQ LTHDVLSQLH AIGVRISLDD FGTGYSSLSY
     LHNFPLQKVK IDRSFLEGID TDRPLTLLRG VARLSADLGM SVVVEGIETN EQLELISVDG
     TVTEAQGYLF SRPVPAVRIR QLLNASHGRQ SDNDPMFAVR GRSIG
//