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Database: UniProt
Entry: H0UKJ4_9BACT
LinkDB: H0UKJ4_9BACT
Original site: H0UKJ4_9BACT 
ID   H0UKJ4_9BACT            Unreviewed;       283 AA.
AC   H0UKJ4;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   08-MAY-2019, entry version 36.
DE   RecName: Full=2-dehydro-3-deoxyphosphooctonate aldolase {ECO:0000256|HAMAP-Rule:MF_00056};
DE            EC=2.5.1.55 {ECO:0000256|HAMAP-Rule:MF_00056};
DE   AltName: Full=3-deoxy-D-manno-octulosonic acid 8-phosphate synthase {ECO:0000256|HAMAP-Rule:MF_00056};
DE   AltName: Full=KDO-8-phosphate synthase {ECO:0000256|HAMAP-Rule:MF_00056};
DE            Short=KDO 8-P synthase {ECO:0000256|HAMAP-Rule:MF_00056};
DE            Short=KDOPS {ECO:0000256|HAMAP-Rule:MF_00056};
DE   AltName: Full=Phospho-2-dehydro-3-deoxyoctonate aldolase {ECO:0000256|HAMAP-Rule:MF_00056};
GN   Name=kdsA {ECO:0000256|HAMAP-Rule:MF_00056};
GN   ORFNames=JonanDRAFT_0825 {ECO:0000313|EMBL:EHM13203.1};
OS   Jonquetella anthropi DSM 22815.
OC   Bacteria; Synergistetes; Synergistia; Synergistales; Synergistaceae;
OC   Jonquetella.
OX   NCBI_TaxID=885272 {ECO:0000313|EMBL:EHM13203.1, ECO:0000313|Proteomes:UP000003806};
RN   [1] {ECO:0000313|EMBL:EHM13203.1, ECO:0000313|Proteomes:UP000003806}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 22815 {ECO:0000313|EMBL:EHM13203.1,
RC   ECO:0000313|Proteomes:UP000003806};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Bruce D., Goodwin L., Pitluck S., Peters L., Mikhailova N.,
RA   Held B., Kyrpides N., Mavromatis K., Ivanova N., Markowitz V.,
RA   Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Gronow S., Wellnitz S.,
RA   Brambilla E., Klenk H.-P., Eisen J.A.;
RT   "The Noncontiguous Finished genome of Jonquetella anthropi DSM
RT   22815.";
RL   Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-arabinose 5-phosphate + H2O + phosphoenolpyruvate = 3-
CC         deoxy-alpha-D-manno-2-octulosonate-8-phosphate + phosphate;
CC         Xref=Rhea:RHEA:14053, ChEBI:CHEBI:15377, ChEBI:CHEBI:43474,
CC         ChEBI:CHEBI:57693, ChEBI:CHEBI:58702, ChEBI:CHEBI:85985;
CC         EC=2.5.1.55; Evidence={ECO:0000256|HAMAP-Rule:MF_00056,
CC         ECO:0000256|SAAS:SAAS01123735};
CC   -!- PATHWAY: Bacterial outer membrane biogenesis; lipopolysaccharide
CC       biosynthesis. {ECO:0000256|SAAS:SAAS00700395}.
CC   -!- PATHWAY: Carbohydrate biosynthesis; 3-deoxy-D-manno-octulosonate
CC       biosynthesis; 3-deoxy-D-manno-octulosonate from D-ribulose 5-
CC       phosphate: step 2/3. {ECO:0000256|HAMAP-Rule:MF_00056,
CC       ECO:0000256|SAAS:SAAS00700401}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00056,
CC       ECO:0000256|SAAS:SAAS00700398}.
CC   -!- SIMILARITY: Belongs to the KdsA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00056, ECO:0000256|SAAS:SAAS00700400}.
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DR   EMBL; CM001376; EHM13203.1; -; Genomic_DNA.
DR   RefSeq; WP_008522890.1; NZ_CM001376.1.
DR   STRING; 885272.JonanDRAFT_0825; -.
DR   EnsemblBacteria; EHM13203; EHM13203; JonanDRAFT_0825.
DR   OrthoDB; 687380at2; -.
DR   BioCyc; JANT885272:G1H1Y-833-MONOMER; -.
DR   UniPathway; UPA00030; -.
DR   UniPathway; UPA00357; UER00474.
DR   Proteomes; UP000003806; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008676; F:3-deoxy-8-phosphooctulonate synthase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0019294; P:keto-3-deoxy-D-manno-octulosonic acid biosynthetic process; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.20.20.70; -; 1.
DR   HAMAP; MF_00056; KDO8P_synth; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006269; KDO8P_synthase.
DR   PANTHER; PTHR21057; PTHR21057; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   TIGRFAMs; TIGR01362; KDO8P_synth; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000003806};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00056,
KW   ECO:0000256|SAAS:SAAS00700397};
KW   Lipopolysaccharide biosynthesis {ECO:0000256|HAMAP-Rule:MF_00056,
KW   ECO:0000256|SAAS:SAAS00700406};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003806};
KW   Transferase {ECO:0000256|HAMAP-Rule:MF_00056,
KW   ECO:0000256|SAAS:SAAS00080156}.
FT   DOMAIN        7    259       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   283 AA;  30519 MW;  93DD5F4A57622FDF CRC64;
     MSVKISNFSI GDGSPLAVIA GPCALESLEL GLQVGGALKE ICSRLGLNYI FKASFDKANR
     TSIHSKRGPG IDQGLEWLGT IKGELDVPVL TDIHESWQAE PVAQVVDVLQ IPAFLCRQTD
     LLVAAAKTGR PVNVKKAQFL APGDMKSVIT KLHEAGNDNV MVCERGTSMG YHQLVVDMRS
     LPIMRSLGRP VVFDATHCVQ MPSGQGDSSG GDRRFTLPLA RAAVAIGVDG LFMEVHPKPE
     EAFSDGPNMV PLSMAERFLT DIATIDRLVR SDLGPVELDW CQK
//
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