ID H0UX69_CAVPO Unreviewed; 701 AA.
AC H0UX69;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 2.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Zinc finger MYND-type containing 15 {ECO:0000313|Ensembl:ENSCPOP00000001675.3};
GN Name=ZMYND15 {ECO:0000313|Ensembl:ENSCPOP00000001675.3};
OS Cavia porcellus (Guinea pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae;
OC Cavia.
OX NCBI_TaxID=10141 {ECO:0000313|Ensembl:ENSCPOP00000001675.3, ECO:0000313|Proteomes:UP000005447};
RN [1] {ECO:0000313|Proteomes:UP000005447}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2N {ECO:0000313|Proteomes:UP000005447};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSCPOP00000001675.3}
RP IDENTIFICATION.
RC STRAIN=2N {ECO:0000313|Ensembl:ENSCPOP00000001675.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAKN02044434; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H0UX69; -.
DR Ensembl; ENSCPOT00000001871.3; ENSCPOP00000001675.3; ENSCPOG00000001850.4.
DR VEuPathDB; HostDB:ENSCPOG00000001850; -.
DR GeneTree; ENSGT00390000000527; -.
DR HOGENOM; CLU_022430_0_0_1; -.
DR TreeFam; TF336410; -.
DR Proteomes; UP000005447; Unassembled WGS sequence.
DR Bgee; ENSCPOG00000001850; Expressed in testis and 1 other cell type or tissue.
DR GO; GO:0042826; F:histone deacetylase binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 6.10.140.2220; -; 1.
DR InterPro; IPR046824; Mss51-like_C.
DR InterPro; IPR042989; ZMY15.
DR InterPro; IPR002893; Znf_MYND.
DR PANTHER; PTHR47085; ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 15; 1.
DR PANTHER; PTHR47085:SF1; ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 15; 1.
DR Pfam; PF20179; MSS51_C; 1.
DR Pfam; PF01753; zf-MYND; 1.
DR SUPFAM; SSF144232; HIT/MYND zinc finger-like; 1.
DR PROSITE; PS50865; ZF_MYND_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000005447};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00134}.
FT DOMAIN 312..358
FT /note="MYND-type"
FT /evidence="ECO:0000259|PROSITE:PS50865"
FT REGION 110..176
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 661..701
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 125..144
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 665..682
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 701 AA; 76818 MW; C36FE8B37F7A354B CRC64;
MEFVSGYRDE FLDFAALLFG WFHKFVAERG PVGASLEGRW RQMEAQIKRL PQDPALWVLH
VLPNNSVGVS LGQGAEPGPG SGLGAARLLG DEPPLHLRDL SPYVSFVSLE DGEEGEQEEE
DERENAGETP PRTEKGEPQE DGEPAPSSRE SPPDAKPPLE PGETEQEAGG EDVCPENRAE
SHTAAAALEK RKGRRSEAGP LHLSCLLLVT DEYGTILGID LLMDRAPGSA DLGSGTKSLA
PRAYILLCHS MACPMGSGDP RKPRQLTVGD VQLHRELESL VSRVKVKLTK TPMRTWGPRP
GFTFASLRAR TCHVCHRHSF EVKLTPCPQC GAVLYCGEAC LRTDWRRCPD DVSHRFWCPK
LAAFMERAGE LATLPFTYTA EVTSETFNKE AFLASRGLTR GYWTQLSMLI PGPGTPRTPR
GSVPSLSLLN GDPYQLLQGD GPALMPPVPS DPPRGPFVPE LNIQNKQSLK IHVVEAGKEF
DLVMVFWELL VLLPHVALEL QFVGDDLPLE SDQQHFTLQR DGPEVSVRPS CGVSARLNSG
TKEKGGRRDL QIKVLARPYH LLQGPKPDLV IGFNSGFGLK DTWLSSLPRL QSLRVPAFFT
ESSEYGCVMD DQTMAVATGG GTSTPRPNPF RSPFRLRAAD NCMPWYCNAF IFHLVYKPAQ
GNGARPAPCP APPAPTPAAP PAPARRRRGE KKAGRGARRR R
//
