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Database: UniProt
Entry: H0V4A5_CAVPO
LinkDB: H0V4A5_CAVPO
Original site: H0V4A5_CAVPO 
ID   H0V4A5_CAVPO            Unreviewed;       830 AA.
AC   H0V4A5;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 2.
DT   16-OCT-2019, entry version 60.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCPOP00000004442};
OS   Cavia porcellus (Guinea pig).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;
OC   Hystricomorpha; Caviidae; Cavia.
OX   NCBI_TaxID=10141 {ECO:0000313|Ensembl:ENSCPOP00000004442};
RN   [1] {ECO:0000313|Ensembl:ENSCPOP00000004442}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2N {ECO:0000313|Ensembl:ENSCPOP00000004442};
RX   PubMed=21993624; DOI=10.1038/nature10530;
RA   Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J.,
RA   Washietl S., Kheradpour P., Ernst J., Jordan G., Mauceli E.,
RA   Ward L.D., Lowe C.B., Holloway A.K., Clamp M., Gnerre S., Alfoldi J.,
RA   Beal K., Chang J., Clawson H., Cuff J., Di Palma F., Fitzgerald S.,
RA   Flicek P., Guttman M., Hubisz M.J., Jaffe D.B., Jungreis I.,
RA   Kent W.J., Kostka D., Lara M., Martins A.L., Massingham T., Moltke I.,
RA   Raney B.J., Rasmussen M.D., Robinson J., Stark A., Vilella A.J.,
RA   Wen J., Xie X., Zody M.C., Baldwin J., Bloom T., Chin C.W., Heiman D.,
RA   Nicol R., Nusbaum C., Young S., Wilkinson J., Worley K.C., Kovar C.L.,
RA   Muzny D.M., Gibbs R.A., Cree A., Dihn H.H., Fowler G., Jhangiani S.,
RA   Joshi V., Lee S., Lewis L.R., Nazareth L.V., Okwuonu G.,
RA   Santibanez J., Warren W.C., Mardis E.R., Weinstock G.M., Wilson R.K.,
RA   Delehaunty K., Dooling D., Fronik C., Fulton L., Fulton B., Graves T.,
RA   Minx P., Sodergren E., Birney E., Margulies E.H., Herrero J.,
RA   Green E.D., Haussler D., Siepel A., Goldman N., Pollard K.S.,
RA   Pedersen J.S., Lander E.S., Kellis M.;
RT   "A high-resolution map of human evolutionary constraint using 29
RT   mammals.";
RL   Nature 478:476-482(2011).
RN   [2] {ECO:0000313|Ensembl:ENSCPOP00000004442}
RP   IDENTIFICATION.
RC   STRAIN=2N {ECO:0000313|Ensembl:ENSCPOP00000004442};
RG   Ensembl;
RL   Submitted (JAN-2012) to UniProtKB.
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DR   EMBL; AAKN02028871; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 10141.ENSCPOP00000004442; -.
DR   Ensembl; ENSCPOT00000004987; ENSCPOP00000004442; ENSCPOG00000004934.
DR   eggNOG; ENOG410ITES; Eukaryota.
DR   eggNOG; ENOG41102KI; LUCA.
DR   GeneTree; ENSGT00940000160527; -.
DR   InParanoid; H0V4A5; -.
DR   TreeFam; TF106455; -.
DR   Proteomes; UP000005447; Unassembled WGS sequence.
DR   Bgee; ENSCPOG00000004934; Expressed in 3 organ(s), highest expression level in brain.
DR   GO; GO:0003714; F:transcription corepressor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd00021; BBOX; 2.
DR   CDD; cd16765; RING-HC_TIF1beta; 1.
DR   Gene3D; 1.20.920.10; -; 1.
DR   Gene3D; 3.30.40.10; -; 1.
DR   InterPro; IPR003649; Bbox_C.
DR   InterPro; IPR001487; Bromodomain.
DR   InterPro; IPR036427; Bromodomain-like_sf.
DR   InterPro; IPR037373; KAP1.
DR   InterPro; IPR042713; TIF1beta_RING-HC.
DR   InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR   InterPro; IPR000315; Znf_B-box.
DR   InterPro; IPR011011; Znf_FYVE_PHD.
DR   InterPro; IPR001965; Znf_PHD.
DR   InterPro; IPR019787; Znf_PHD-finger.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR25462:SF274; PTHR25462:SF274; 1.
DR   Pfam; PF00628; PHD; 1.
DR   Pfam; PF00643; zf-B_box; 2.
DR   Pfam; PF14634; zf-RING_5; 1.
DR   SMART; SM00502; BBC; 1.
DR   SMART; SM00336; BBOX; 2.
DR   SMART; SM00297; BROMO; 1.
DR   SMART; SM00249; PHD; 1.
DR   SMART; SM00184; RING; 2.
DR   SUPFAM; SSF57903; SSF57903; 1.
DR   PROSITE; PS50119; ZF_BBOX; 2.
DR   PROSITE; PS01359; ZF_PHD_1; 1.
DR   PROSITE; PS50016; ZF_PHD_2; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005447};
KW   Metal-binding {ECO:0000256|SAAS:SAAS01011399};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005447};
KW   Zinc {ECO:0000256|SAAS:SAAS01006535};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00146,
KW   ECO:0000256|SAAS:SAAS01007077}.
FT   DOMAIN       63    116       RING-type. {ECO:0000259|PROSITE:PS50089}.
FT   DOMAIN      143    190       B box-type. {ECO:0000259|PROSITE:
FT                                PS50119}.
FT   DOMAIN      199    240       B box-type. {ECO:0000259|PROSITE:
FT                                PS50119}.
FT   DOMAIN      620    667       PHD-type. {ECO:0000259|PROSITE:PS50016}.
FT   REGION       18     53       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      406    477       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      582    614       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      806    830       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS    426    441       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    816    830       Polar. {ECO:0000256|SAM:MobiDB-lite}.
SQ   SEQUENCE   830 AA;  88425 MW;  FEBA2DA8EB179BD8 CRC64;
     LGAVVGVKMA ASMAAAASAT SGSASSGEGS AGGENRAAAS SAAASASSPT AGGGEALELL
     ERCGACRERL RPEREPRLLP CLHSACSACL APSAANSTGD GGPAGDGAVV DCPVCKQQCC
     FKDIVENYFV RDSGNKAASD AQEANQCCTS CEDNAPATSY CVECSEPLCE TCVEAHQRVK
     YTKDHTVRPT GPAKSRDGER TVYCNVHKRE PLVLFCESCD TLTCRDCQLS AHKDHQYQFL
     EDAVRDQRKL LAALVKRLGD KHATLQKSTK EVRSSIRQVS DVQKRVQVDV KMAILQIMKE
     LNKRGRVLVS DAQKLTEGQQ ERLERQHWSM TKIQKHQEHI LRFASWALES DNNTALLLSK
     KLIYFQLQRA LKMIVEPVEP HGEMKFQWDL SAWTKSAEAF GKIVAERPGT NSTGPAPMAP
     PRALGPLSKQ SSSSSQPMEV QEGYGCESDD PYSSAEPHVS GMKRSSSGEG EVSGRMRKVP
     RVSLERLDLD LTGDSQPPVF KVFPGTTTED YNLIVIERGG AAAAAAGQPG TAPPGAAGAP
     PLPSMAIVKE EEMEAAIGAP PAAAVAPATK PVLMALAEGP AAEGPRLASP SGSTSSGLEV
     VAPEGSTAPG GDPGTLDDSA TICRVCQKPG DLVMCNQCEF CFHLDCHLPA LQDVPGEEWS
     CSLCHVPPEL KEEDGTLSMD GADSTGIVAK LSPINQQKCE RVLLALFCHE PCRPLHQLAT
     DSPFSMEQPG GTLDLTLIRA RLQEKLSPPY SSPQEFAEDV GRMFKQFNKL TEDKADVQSI
     IGLQRFFESR LNEAFGDTKF SAVLVEPPPL SLPGAGPSSQ ELSGGPSDGP
//
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