ID H0V9L9_CAVPO Unreviewed; 200 AA.
AC H0V9L9;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=LHFPL tetraspan subfamily member 6 {ECO:0000313|Ensembl:ENSCPOP00000006518.2};
GN Name=LHFPL6 {ECO:0000313|Ensembl:ENSCPOP00000006518.2};
OS Cavia porcellus (Guinea pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae;
OC Cavia.
OX NCBI_TaxID=10141 {ECO:0000313|Ensembl:ENSCPOP00000006518.2, ECO:0000313|Proteomes:UP000005447};
RN [1] {ECO:0000313|Proteomes:UP000005447}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2N {ECO:0000313|Proteomes:UP000005447};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSCPOP00000006518.2}
RP IDENTIFICATION.
RC STRAIN=2N {ECO:0000313|Ensembl:ENSCPOP00000006518.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AAKN02010668; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAKN02010669; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAKN02010670; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAKN02010671; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAKN02010672; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003477485.1; XM_003477437.3.
DR RefSeq; XP_012996699.1; XM_013141245.1.
DR AlphaFoldDB; H0V9L9; -.
DR STRING; 10141.ENSCPOP00000006518; -.
DR Ensembl; ENSCPOT00000007306.3; ENSCPOP00000006518.2; ENSCPOG00000007234.4.
DR GeneID; 100729490; -.
DR KEGG; cpoc:100729490; -.
DR CTD; 10186; -.
DR VEuPathDB; HostDB:ENSCPOG00000007234; -.
DR eggNOG; KOG4026; Eukaryota.
DR GeneTree; ENSGT00990000203589; -.
DR HOGENOM; CLU_084868_2_0_1; -.
DR InParanoid; H0V9L9; -.
DR OMA; PVHDENR; -.
DR OrthoDB; 2917854at2759; -.
DR TreeFam; TF321143; -.
DR Proteomes; UP000005447; Unassembled WGS sequence.
DR Bgee; ENSCPOG00000007234; Expressed in cerebellum and 13 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 1.20.140.150; -; 1.
DR InterPro; IPR019372; LHFPL.
DR PANTHER; PTHR12489:SF12; LHFPL TETRASPAN SUBFAMILY MEMBER 6 PROTEIN; 1.
DR PANTHER; PTHR12489; LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN; 1.
DR Pfam; PF10242; L_HMGIC_fpl; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005447};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 87..108
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 120..141
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 168..190
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 200 AA; 21658 MW; 4C9EF6FD167205F1 CRC64;
MASSLTCTGV IWAFLSFLCA ATSCVGFFMP YWLWGSQLGK PVSFGTFRRC SYPVHDESRQ
MMVMVEECGR YASFQGIPST EWRICTIVTG LGCGLLLLVA LTALMGCCVS ELISRTVGRV
AGGIQFLGGL LIGAGCALYP LGWDSEEVRQ TCGYISGQFD LGKCEIGWAY YCTGAGAAAA
MLLCTWLACF SGKKQKHYPY
//
