ID H0VG98_CAVPO Unreviewed; 671 AA.
AC H0VG98;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 2.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=Kinesin associated protein 3 {ECO:0008006|Google:ProtNLM};
OS Cavia porcellus (Guinea pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae;
OC Cavia.
OX NCBI_TaxID=10141 {ECO:0000313|Ensembl:ENSCPOP00000009125.3, ECO:0000313|Proteomes:UP000005447};
RN [1] {ECO:0000313|Proteomes:UP000005447}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2N {ECO:0000313|Proteomes:UP000005447};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSCPOP00000009125.3}
RP IDENTIFICATION.
RC STRAIN=2N {ECO:0000313|Ensembl:ENSCPOP00000009125.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAKN02037462; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAKN02037463; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAKN02037464; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAKN02037465; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H0VG98; -.
DR STRING; 10141.ENSCPOP00000009125; -.
DR Ensembl; ENSCPOT00000010254.3; ENSCPOP00000009125.3; ENSCPOG00000010161.4.
DR VEuPathDB; HostDB:ENSCPOG00000010161; -.
DR eggNOG; KOG1222; Eukaryota.
DR GeneTree; ENSGT00390000003574; -.
DR HOGENOM; CLU_009879_1_0_1; -.
DR InParanoid; H0VG98; -.
DR OMA; MYELNIV; -.
DR TreeFam; TF314964; -.
DR Proteomes; UP000005447; Unassembled WGS sequence.
DR Bgee; ENSCPOG00000010161; Expressed in testis and 12 other cell types or tissues.
DR GO; GO:0005871; C:kinesin complex; IEA:InterPro.
DR GO; GO:0019894; F:kinesin binding; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR008658; KAP3.
DR PANTHER; PTHR15605:SF2; KINESIN-ASSOCIATED PROTEIN 3; 1.
DR PANTHER; PTHR15605; KINESIN-ASSOCIATED PROTEINS; 1.
DR Pfam; PF05804; KAP; 1.
DR SMART; SM00185; ARM; 3.
DR SMART; SM01297; KAP; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50176; ARM_REPEAT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005447}.
FT REPEAT 565..609
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REGION 87..109
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 87..107
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 671 AA; 77669 MW; 3A5F3F4616A95985 CRC64;
NIDVHPSEKA LIVQYEVEAT ILGEMGDPML GERKECQKII RLKGLNANTD ITSLARKVVE
ECKLIHPSKL NEVEQLLYYL QNRRDSLSGK EKKEKSNKPK DPPPFEGTEI DEVANINDMD
EYLELLYEDI PDKVRGSALI LQLARNPDNL EELLLNETAL GALARVLRED WKKLLKLLLL
SFSQFHGVIT HYKIGALCMN IIDHELKRHE LWQEELSKKK KFLLDEDLEN QTLKKEYEKT
FKKYQGLVVK QEQLLRVALY LLLNLAEDTR TELKMRNKNI VHMLVKALDR DNFELLILVV
TFLKKLSIFM ENKNDMVEMD IVEKLVKLVP CEHEDLLNIT LRLLLNLSFD TGLRNKMVQV
GLLPKLTALL GNENYKQIAI CVLYHISMDD RFKSMFAYTD CIPQLMKMLF ECSDERIDLE
LISLCINLAA NKRNVQLICE GNGLKMLMKR ALKFKDPLLM KMIRNISQHD GPTKNLFIDY
VGDLAAQISN DEEEEFVIEC LGTLANLTIP DLDWELVLKE YKLVPYLKDK LKPGAAEDDL
VLEVVIMIGT VSMDDSCAAL LAKSGIIPAL IELLNAQQED DEFVCQIIYV FYQMVFHQAT
RDVIIKETQA PAYLIDLMHD KNNEIRKVCD NTLDIIAEYD DEWAKKIQRE KFCWHNSQWL
EMVESRQMDE S
//
