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Database: UniProt
Entry: H0VI84_CAVPO
LinkDB: H0VI84_CAVPO
Original site: H0VI84_CAVPO 
ID   H0VI84_CAVPO            Unreviewed;       477 AA.
AC   H0VI84;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 2.
DT   17-JUN-2020, entry version 37.
DE   SubName: Full=Tubulin epsilon and delta complex 1 {ECO:0000313|Ensembl:ENSCPOP00000009896};
GN   Name=TEDC1 {ECO:0000313|Ensembl:ENSCPOP00000009896};
OS   Cavia porcellus (Guinea pig).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae;
OC   Cavia.
OX   NCBI_TaxID=10141 {ECO:0000313|Ensembl:ENSCPOP00000009896, ECO:0000313|Proteomes:UP000005447};
RN   [1] {ECO:0000313|Ensembl:ENSCPOP00000009896, ECO:0000313|Proteomes:UP000005447}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2N {ECO:0000313|Ensembl:ENSCPOP00000009896,
RC   ECO:0000313|Proteomes:UP000005447};
RX   PubMed=21993624; DOI=10.1038/nature10530;
RA   Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA   Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA   Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA   Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA   Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA   Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA   Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA   Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA   Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA   Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA   Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA   Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA   Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA   Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA   Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT   "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL   Nature 478:476-482(2011).
RN   [2] {ECO:0000313|Ensembl:ENSCPOP00000009896}
RP   IDENTIFICATION.
RC   STRAIN=2N {ECO:0000313|Ensembl:ENSCPOP00000009896};
RG   Ensembl;
RL   Submitted (JAN-2012) to UniProtKB.
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DR   EMBL; AAKN02052009; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_005000629.1; XM_005000572.2.
DR   Ensembl; ENSCPOT00000011111; ENSCPOP00000009896; ENSCPOG00000011010.
DR   GeneID; 100717056; -.
DR   CTD; 283643; -.
DR   eggNOG; ENOG410IWUX; Eukaryota.
DR   eggNOG; ENOG4111XJF; LUCA.
DR   GeneTree; ENSGT00390000011474; -.
DR   HOGENOM; CLU_052124_0_0_1; -.
DR   InParanoid; H0VI84; -.
DR   OrthoDB; 1248596at2759; -.
DR   TreeFam; TF330945; -.
DR   Proteomes; UP000005447; Unassembled WGS sequence.
DR   Bgee; ENSCPOG00000011010; Expressed in liver and 2 other tissues.
DR   GO; GO:0005814; C:centriole; IEA:Ensembl.
DR   GO; GO:0005929; C:cilium; IEA:Ensembl.
DR   GO; GO:0045880; P:positive regulation of smoothened signaling pathway; IEA:Ensembl.
DR   InterPro; IPR027996; DUF4509.
DR   InterPro; IPR028100; DUF4510.
DR   Pfam; PF14970; DUF4509; 2.
DR   Pfam; PF14971; DUF4510; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005447}.
FT   DOMAIN          49..199
FT                   /note="DUF4509"
FT                   /evidence="ECO:0000259|Pfam:PF14970"
FT   DOMAIN          242..273
FT                   /note="DUF4509"
FT                   /evidence="ECO:0000259|Pfam:PF14970"
FT   DOMAIN          311..475
FT                   /note="DUF4510"
FT                   /evidence="ECO:0000259|Pfam:PF14971"
FT   COILED          333..360
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   477 AA;  53211 MW;  BB32BFF739821FE1 CRC64;
     MGRRRRQVRE EASAWAAAGT RTLPDAIAAL SRSLPAGPSP EIFRRAKFDR PEAAPELWRL
     LFRVLSPLLA DRAAASPGLG AQACWVKAVL CYHGYPRSAL AQLPEDGSQG SRELLLALSW
     LLARGPLLEW LLAQTCVQLG DQVPTFEYEV LAIPRLAAPQ MDAEGPVDIR HLQWLMGKLH
     FRWQNLISIQ QEQCALLSKG SAVLSRGCFF LPAAIGDRSV PSRACHFADG MEGPAALCHT
     PQIHTYTFGC HSDQNLGHLS VTETETLRDP EGSQQLLQVL EQENARLEAA LEWRRYELVF
     WQWMDTVLGA CPPEDPSVPS FQPRIPEHGR GKLELVAREL QALKEELQVL QKLLHEEVLS
     RRQAWETRVG ALGHGPEWST SRQDLQQAVE QELLALQQSW KQDRYPSLPR RRHRLVKIEA
     GAAGAQGLPV AEVIRGLKSQ EASLEVVLCQ LQGQCRQELA RLVGTMPGLI WILPPGR
//
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