ID H0VJ09_CAVPO Unreviewed; 510 AA.
AC H0VJ09;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 2.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 {ECO:0000313|Ensembl:ENSCPOP00000010221.3};
GN Name=SMARCD2 {ECO:0000313|Ensembl:ENSCPOP00000010221.3};
OS Cavia porcellus (Guinea pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae;
OC Cavia.
OX NCBI_TaxID=10141 {ECO:0000313|Ensembl:ENSCPOP00000010221.3, ECO:0000313|Proteomes:UP000005447};
RN [1] {ECO:0000313|Proteomes:UP000005447}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2N {ECO:0000313|Proteomes:UP000005447};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSCPOP00000010221.3}
RP IDENTIFICATION.
RC STRAIN=2N {ECO:0000313|Ensembl:ENSCPOP00000010221.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the SMARCD family.
CC {ECO:0000256|ARBA:ARBA00010619}.
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DR EMBL; AAKN02045211; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H0VJ09; -.
DR STRING; 10141.ENSCPOP00000010221; -.
DR Ensembl; ENSCPOT00000011477.3; ENSCPOP00000010221.3; ENSCPOG00000011371.4.
DR VEuPathDB; HostDB:ENSCPOG00000011371; -.
DR GeneTree; ENSGT00940000158654; -.
DR HOGENOM; CLU_023529_0_2_1; -.
DR InParanoid; H0VJ09; -.
DR OMA; MPTQRRG; -.
DR TreeFam; TF106486; -.
DR Proteomes; UP000005447; Unassembled WGS sequence.
DR Bgee; ENSCPOG00000011371; Expressed in adrenal gland and 13 other cell types or tissues.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0016514; C:SWI/SNF complex; IEA:Ensembl.
DR GO; GO:0006337; P:nucleosome disassembly; IEA:Ensembl.
DR CDD; cd17675; SWIB_BAF60B; 1.
DR Gene3D; 1.10.245.10; SWIB/MDM2 domain; 1.
DR InterPro; IPR030090; SMARCD2_SWIB_dom.
DR InterPro; IPR019835; SWIB_domain.
DR InterPro; IPR036885; SWIB_MDM2_dom_sf.
DR InterPro; IPR003121; SWIB_MDM2_domain.
DR PANTHER; PTHR13844; SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D; 1.
DR PANTHER; PTHR13844:SF2; SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D MEMBER 2; 1.
DR Pfam; PF02201; SWIB; 1.
DR SMART; SM00151; SWIB; 1.
DR SUPFAM; SSF47592; SWIB/MDM2 domain; 1.
DR PROSITE; PS51925; SWIB_MDM2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000005447}.
FT DOMAIN 285..362
FT /note="DM2"
FT /evidence="ECO:0000259|PROSITE:PS51925"
FT REGION 1..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 184..205
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 510 AA; 57507 MW; DB4E4BF8C216B8CC CRC64;
MSGRGAGGSP LPPAAYPRRD PGMLPGPALR GPGPAGGVGA PWGCRLPPHG PRGSPRLQYQ
RPGMSPGNRM PMAGLQVGPP TGSPFGTAVP LRPGMPPTMM DPFRKRLLVP QAQPPMPAQR
RGRVKQAIRE LVPESQAYMD LLAFERKLDQ TIARKRMEIQ EAIKKPLTQK RKLRIYISNT
FSPSKAEGDS VGTAGTSGGT PAGDKVASWE LRVEGKLLDD PSKQKRKFSS FFKSLVIELD
KELYGPDNHL VEWHRMPTTQ ETDGFQVKRP GDLNVKCTLL LMLDHQPPQY KLDPRLARLL
GVHTQTRAAI MQALWLYIKH NQLQDGHERE YINCNRYFRQ IFSCGRLRFS EIPMKLAGLL
QHPDPIVINH VISVDPNDQK KTACYDIDVE VDDPLKAQMS NFLASTTNQQ EIASLDVKIH
ETIESINQLK TQRDFMLSFS TDPQDFIQEW LRSQRRDLKI ITDVIGNPEE ERRAAFYHQP
WAQEAVGRHI FAKVQQRRQE LEQVLGIRLT
//
