ID H0VZZ3_CAVPO Unreviewed; 252 AA.
AC H0VZZ3;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 2.
DT 27-MAR-2024, entry version 63.
DE RecName: Full=Fibroblast growth factor {ECO:0000256|RuleBase:RU049442};
DE Short=FGF {ECO:0000256|RuleBase:RU049442};
GN Name=FGF14 {ECO:0000313|Ensembl:ENSCPOP00000016277.2};
OS Cavia porcellus (Guinea pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae;
OC Cavia.
OX NCBI_TaxID=10141 {ECO:0000313|Ensembl:ENSCPOP00000016277.2, ECO:0000313|Proteomes:UP000005447};
RN [1] {ECO:0000313|Proteomes:UP000005447}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2N {ECO:0000313|Proteomes:UP000005447};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSCPOP00000016277.2}
RP IDENTIFICATION.
RC STRAIN=2N {ECO:0000313|Ensembl:ENSCPOP00000016277.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the heparin-binding growth factors family.
CC {ECO:0000256|ARBA:ARBA00007936, ECO:0000256|RuleBase:RU049442}.
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DR EMBL; AAKN02008573; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAKN02008574; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAKN02008575; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAKN02008576; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAKN02008577; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAKN02008578; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H0VZZ3; -.
DR STRING; 10141.ENSCPOP00000016277; -.
DR Ensembl; ENSCPOT00000020761.2; ENSCPOP00000016277.2; ENSCPOG00000024889.2.
DR VEuPathDB; HostDB:ENSCPOG00000024889; -.
DR eggNOG; KOG3885; Eukaryota.
DR GeneTree; ENSGT00940000156984; -.
DR HOGENOM; CLU_081609_2_0_1; -.
DR InParanoid; H0VZZ3; -.
DR OMA; KRINSPH; -.
DR TreeFam; TF317805; -.
DR Proteomes; UP000005447; Unassembled WGS sequence.
DR Bgee; ENSCPOG00000024889; Expressed in testis and 6 other cell types or tissues.
DR GO; GO:0008083; F:growth factor activity; IEA:InterPro.
DR CDD; cd00058; FGF; 1.
DR Gene3D; 2.80.10.50; -; 1.
DR InterPro; IPR002209; Fibroblast_GF_fam.
DR InterPro; IPR008996; IL1/FGF.
DR PANTHER; PTHR11486; FIBROBLAST GROWTH FACTOR; 1.
DR PANTHER; PTHR11486:SF18; FIBROBLAST GROWTH FACTOR 14; 1.
DR Pfam; PF00167; FGF; 1.
DR PRINTS; PR00263; HBGFFGF.
DR PRINTS; PR00262; IL1HBGF.
DR SMART; SM00442; FGF; 1.
DR SUPFAM; SSF50353; Cytokine; 1.
DR PROSITE; PS00247; HBGF_FGF; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000005447}.
FT REGION 219..252
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 226..252
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 252 AA; 28466 MW; 305B0FDA7B56D577 CRC64;
MVKPVPLFRR TDFKLLLCNH KDLFFLRVSK LLDCFSPKSM WFLWNIFSKG THMLQCLCGK
SLKKNKNPTD PQLKGIVTRL YCRQGYYLQM HPDGALDGTK DDSTNSTLFN LIPVGLRVVA
IQGVKTGLYI AMNGEGYLYP SELFTPECKF KESVFENYYV IYSSMLYRQQ ESGRAWFLGL
NKEGQAMKGN RVKKTKPAAH FLPKPLEVAM YREPSLHDVG ETVPKTGVTP SKSTSASAIM
NGGKPVNKSK TT
//
