ID H0W6Y6_CAVPO Unreviewed; 319 AA.
AC H0W6Y6;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 2.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Embigin {ECO:0000313|Ensembl:ENSCPOP00000018740.2};
GN Name=EMB {ECO:0000313|Ensembl:ENSCPOP00000018740.2};
OS Cavia porcellus (Guinea pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae;
OC Cavia.
OX NCBI_TaxID=10141 {ECO:0000313|Ensembl:ENSCPOP00000018740.2, ECO:0000313|Proteomes:UP000005447};
RN [1] {ECO:0000313|Proteomes:UP000005447}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2N {ECO:0000313|Proteomes:UP000005447};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSCPOP00000018740.2}
RP IDENTIFICATION.
RC STRAIN=2N {ECO:0000313|Ensembl:ENSCPOP00000018740.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAKN02031604; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAKN02031605; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAKN02031606; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAKN02031607; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H0W6Y6; -.
DR STRING; 10141.ENSCPOP00000018740; -.
DR Ensembl; ENSCPOT00000025584.2; ENSCPOP00000018740.2; ENSCPOG00000019838.2.
DR VEuPathDB; HostDB:ENSCPOG00000019838; -.
DR eggNOG; ENOG502RYF2; Eukaryota.
DR GeneTree; ENSGT00940000158944; -.
DR HOGENOM; CLU_065379_0_0_1; -.
DR InParanoid; H0W6Y6; -.
DR OMA; KGSYWCH; -.
DR TreeFam; TF326759; -.
DR Proteomes; UP000005447; Unassembled WGS sequence.
DR Bgee; ENSCPOG00000019838; Expressed in uterine cervix and 10 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00096; Ig; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR PANTHER; PTHR10075; BASIGIN RELATED; 1.
DR PANTHER; PTHR10075:SF4; EMBIGIN; 1.
DR Pfam; PF13927; Ig_3; 1.
DR SMART; SM00409; IG; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR PROSITE; PS50835; IG_LIKE; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005447};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..32
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 33..319
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012497497"
FT TRANSMEM 256..276
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 43..133
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 150..245
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 281..319
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 281..298
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 299..319
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 319 AA; 35009 MW; F0AE39FD550B21A4 CRC64;
MLPGAGLFGA PAARPPLWLL LLLLCVVAAA RGDPTNGGPA GSPGVMALES HNISLNEHSS
EPVEKIVTLA SPSVMSLTCK FKTSENLASV SVSWRKDGNE SVTNYSRTAA EDTVSTQYNF
TIVDSRQMGN YSCLFEERKK YRGTFDIKVP KLGGKNKPLI TYVGDSTVLV CKCEKCFPVH
WTWYRSNGSV QVPIDPVNDT KYAVTGGNSN ETKLKIKDLL EEDGGSYWCR AEFPLGDSED
QLELVVLSFL VPLKPFFAII AEAVVLVAVI LLCEVYTQKK RNHPDDGKEF EQIEQLKSDD
SNGIENNAPR QRKNESAGQ
//
