ID H0WI60_OTOGA Unreviewed; 1016 AA.
AC H0WI60;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Glutamate receptor interacting protein 1 {ECO:0000313|Ensembl:ENSOGAP00000001098.2};
GN Name=GRIP1 {ECO:0000313|Ensembl:ENSOGAP00000001098.2};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000001098.2, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000001098.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAQR03146760; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03146761; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03146762; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03146763; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03146764; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03146765; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03146766; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03146767; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03146768; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03146769; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H0WI60; -.
DR STRING; 30611.ENSOGAP00000001098; -.
DR Ensembl; ENSOGAT00000001227.2; ENSOGAP00000001098.2; ENSOGAG00000001224.2.
DR eggNOG; KOG3528; Eukaryota.
DR GeneTree; ENSGT00940000158692; -.
DR HOGENOM; CLU_004313_0_0_1; -.
DR InParanoid; H0WI60; -.
DR OMA; QGGIAAX; -.
DR TreeFam; TF326909; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR CDD; cd00992; PDZ_signaling; 7.
DR Gene3D; 2.30.42.10; -; 7.
DR InterPro; IPR043545; GRIP1/2.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR041489; PDZ_6.
DR InterPro; IPR036034; PDZ_sf.
DR PANTHER; PTHR46227:SF3; GLUTAMATE RECEPTOR-INTERACTING PROTEIN 1; 1.
DR PANTHER; PTHR46227; GLUTAMATE RECEPTOR-INTERACTING PROTEIN GRIP; 1.
DR Pfam; PF00595; PDZ; 5.
DR Pfam; PF17820; PDZ_6; 1.
DR SMART; SM00228; PDZ; 7.
DR SUPFAM; SSF50156; PDZ domain-like; 7.
DR PROSITE; PS50106; PDZ; 7.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005225}.
FT DOMAIN 10..93
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 107..195
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 209..293
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 377..452
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 478..563
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 578..660
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 894..974
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 659..711
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 746..790
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 826..874
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 753..776
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 826..867
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1016 AA; 108970 MW; 49BEB94767A46A20 CRC64;
LTEEFKGSTV VELMKKEGTT LGLTVSGGID KDGKPRVSNL RQGGIAARSD QLDVGDYIKA
VNGINLAKFR HDEIISLLKN VGERVVLEVE YELPPVAVQG SSVIFRTVEV TLHKEGNTFG
FVIRGGAHDD RNKSRPVVIT CVRPGGPADR EGTIKPGDRL LSVDGIRLLG TTHAEAMSIL
KQCGQEATLL IEYDVSVMDS VATASGPLLV EVAKAPGASL GVALTASMCC DRQVIVIDKI
KSASIADRCG ALHVGDHVLS IDGTSTEHCT LAEATQFLAN TTDQVKLEIL PHHQTRLALK
GPDHAALVSS SFSPTSMSAY SLSSLNMGTL PRSLYSTSPR GTMMRRRVKK KDFKSSLSLA
SSTVGLAGQV VHTETTEVVL TADPVMGFGI QLQGSVFATE TLSSPPLISY IEADSPAERC
GVLQIGDRVV AINGVPTEDS TFEEANQLLR DSSITSKVTL EIEFDVAESV IPSSGTFHVK
LPKKHSVELG ITISSPSSRK PGDPLVISDI KKGSVAHRTG TLELGDKLLA IDNIRLDNCS
MEDAVQILQQ CEDLVKLKIR KDEDNSDEQE SSGAIIYTVE LKRYGGPLGI TISGTEEPFD
PIIISSLTKG GLAERTGAIH VGDRILAINS SSLKGKPLSE AIHLLQMAGE TVTLKIKKQT
DAQSASSPKK FPLASHMSDL GDTEEDSPPA QKPGKLSDMY PSTVPSVDSA VDSWDGSAVD
TSYGTHGAGF QAPGYNFNTY DWRSPKPRSS LSPGCKPRSQ TYPDVGLSSE DWDQSTASGF
EGAPEGTDAE REESFWSQAL EDLETCGQSG ILRELEATIM SGSTLSLNRE APTARSQLGR
QASFQERGSA RPHYSQTTRS NTLPSDVGRK SVPLRKVKQD MKEVVSQTPV ELHKVTLYKG
SDMEDFGFSV ADGLLEKGVY VKNIRPAGPG DLGGLKPYTL QVNHVRTRDF DCCLVVPLIA
ESGSRLDLVI SRSPVAAQKP VEQALPGGDW SEQNCAFFQQ PRHGGNLEAR EPTNTL
//
