ID   H0WJ75_OTOGA            Unreviewed;       704 AA.
AC   H0WJ75;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   27-MAR-2024, entry version 50.
DE   RecName: Full=Lebercilin-like protein {ECO:0000256|ARBA:ARBA00041189};
DE   AltName: Full=Leber congenital amaurosis 5-like protein {ECO:0000256|ARBA:ARBA00041402};
GN   Name=LCA5L {ECO:0000313|Ensembl:ENSOGAP00000001531.2};
OS   Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC   Galagidae; Otolemur.
OX   NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000001531.2, ECO:0000313|Proteomes:UP000005225};
RN   [1] {ECO:0000313|Proteomes:UP000005225}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   The Broad Institute Genome Sequencing Platform;
RA   Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA   Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA   Walker B.J., Sharpe T., Hall G.;
RT   "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL   Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSOGAP00000001531.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the LCA5 family.
CC       {ECO:0000256|ARBA:ARBA00010229}.
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DR   EMBL; AAQR03164301; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03164302; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03164303; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03164304; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03164305; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; H0WJ75; -.
DR   STRING; 30611.ENSOGAP00000001531; -.
DR   Ensembl; ENSOGAT00000001718.2; ENSOGAP00000001531.2; ENSOGAG00000001718.2.
DR   eggNOG; ENOG502QQSE; Eukaryota.
DR   GeneTree; ENSGT00560000077266; -.
DR   HOGENOM; CLU_026861_0_0_1; -.
DR   InParanoid; H0WJ75; -.
DR   OMA; MKHQETQ; -.
DR   TreeFam; TF323306; -.
DR   Proteomes; UP000005225; Unassembled WGS sequence.
DR   InterPro; IPR026188; Lebercilin-like.
DR   InterPro; IPR028933; Lebercilin_dom.
DR   PANTHER; PTHR16650; C21ORF13-RELATED; 1.
DR   PANTHER; PTHR16650:SF9; LEBERCILIN-LIKE PROTEIN; 1.
DR   Pfam; PF15619; Lebercilin; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005225}.
FT   DOMAIN          141..333
FT                   /note="Lebercilin"
FT                   /evidence="ECO:0000259|Pfam:PF15619"
FT   REGION          14..54
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          92..114
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          573..629
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          146..173
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          202..286
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        39..54
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        573..594
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   704 AA;  80761 MW;  4F73A0462E1CF1C5 CRC64;
     IRLFTMADPT NTNVNEHFPS VALENSRKSA EFERSPGAAD FSTNGNDSDK SVDYSRSQCS
     CRSLSSHRDY SEDFISDCSE IAISRNYLKQ PVAKEKEKKK HVSKVSQPKG QKEISVEKKH
     IRNASFVNSQ ISAINQRRDA MTHRILSARL HKIKELKNEL AEIHRKSEAI IIENQFLKQL
     QLRHVKAIGK YENSKTNLPQ IIINHQNEVK NLRQLLRKSQ EKERTVSRKL RETDSDLLRT
     KDALQALQKL SEDKNLAERD ELTQRLSVLT TKMEANDKKI QSLEKQLRLN SRAFSRQLAI
     ENRKIIGAQT ATKTLQVEVK RLQQKLKEKD RELEIKNIYT NRILKNLYDK EDYPKVSSTK
     SVQADRKILS FTNMRHQETQ KSDDVPCLTT KGKKATGNIG YKEKSTEINH EKSLHISKLL
     KQEDSKRKYE GNFNNFKACT LPHKSNNLVL YASVFLFFLS FQSSCQEIDL SKEEEHLKVQ
     LTLENTERQK EKKVDQEKAI LMNEQELPPK RIQVIDPETE SNQEDTAKEK IKRSVQINDV
     NETPDKYAVP CVKTPFRQRK HYSFTTTIEN LHHGLPTSGV PANTGNTRVS NNTSKHRSQT
     EDMKQEHSVS GYEPSFSKSS RIKAKDTTFR DKKSSLMEEL FGSGYVLKNN QSSPVVMKRS
     DQTLNRASAS NAFGDSKVTV VNSIKSSSPT EGKTLELCCN LKTW
//