ID H0WJP2_OTOGA Unreviewed; 636 AA.
AC H0WJP2;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE SubName: Full=Tripartite motif containing 47 {ECO:0000313|Ensembl:ENSOGAP00000001728.2};
GN Name=TRIM47 {ECO:0000313|Ensembl:ENSOGAP00000001728.2};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000001728.2, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000001728.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAQR03041461; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003786170.1; XM_003786122.2.
DR AlphaFoldDB; H0WJP2; -.
DR STRING; 30611.ENSOGAP00000001728; -.
DR Ensembl; ENSOGAT00000001938.2; ENSOGAP00000001728.2; ENSOGAG00000001935.2.
DR GeneID; 100945125; -.
DR KEGG; oga:100945125; -.
DR CTD; 91107; -.
DR eggNOG; KOG2177; Eukaryota.
DR GeneTree; ENSGT00940000154334; -.
DR HOGENOM; CLU_013137_0_2_1; -.
DR InParanoid; H0WJP2; -.
DR OMA; CLESRDY; -.
DR OrthoDB; 5322335at2759; -.
DR TreeFam; TF351086; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:Ensembl.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:Ensembl.
DR CDD; cd19842; Bbox1_TRIM25-like_C-IV; 1.
DR CDD; cd19769; Bbox2_TRIM16-like; 1.
DR CDD; cd15808; SPRY_PRY_TRIM47; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 4.10.830.40; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR042780; TRIM47_SPRY_PRY.
DR InterPro; IPR027370; Znf-RING_euk.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR25465; B-BOX DOMAIN CONTAINING; 1.
DR PANTHER; PTHR25465:SF21; E3 UBIQUITIN-PROTEIN LIGASE TRIM47; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF13445; zf-RING_UBOX; 1.
DR SMART; SM00336; BBOX; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000005225};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 9..58
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 175..215
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 408..629
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT REGION 79..117
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 383..413
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 86..117
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 636 AA; 69410 MW; 1ECBC1B84E2A5124 CRC64;
MDSSGPFSCP ICREPLREPV TLPCGHNFCL ACLGVLWPHR GSGGAGGPGG AARCPLCQEP
FPDGLQLRKN HTLSELLQLR QGSGPGPGPG PAPAPEPSAP SAPPSTPEPS APCAPEPWPA
GEEPVPCDAC PEGAALPAAL SCLSCLASFC PAHLGPHERS PALRGHRLVP PLRRLEESLC
PRHLRPLERY CRAERVCLCE ACAAQEHRGH ELVPLEQERA LQEAEQPKVL SAVEDRMDEL
GAGIAQARRT VALIKSAAVA ERERVSRLFA EAAITLQGFQ NQVLGFIEEG EAAMLGRSQG
DLRRQEEQRS RLTRARHNLN QVPEADSVSF LQELLALRLA LEEGCGPGPG PPRELSFTKS
SQAVRAVRDV LAEVCASQWE QLQGLGSDED GPQKLGSEAD AESQDPDSTN QLESEAPRDY
FLKFAYIVDL DSDTADKFLQ LFGTKGVKRV LCPINYPESP TRFTHCEQVL GEGALDRGTY
YWEVEIIEGW VSVGVMAEGF NPQEPYDRGR LGRNAHSCCL QWNGRSFSVW FHGLEAPLPQ
PFSPTVGICL EYADRALAFY AVRDGKMSLL RRLKASRPRR SGIPASPVDP FQSRLDSHFA
GLFTHRLKPA FFLESVDAHL QIGPLKKSCI SVLKRR
//
