ID H0WKB9_OTOGA Unreviewed; 1811 AA.
AC H0WKB9;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=Collagen type XI alpha 1 chain {ECO:0000313|Ensembl:ENSOGAP00000002004.2};
GN Name=COL11A1 {ECO:0000313|Ensembl:ENSOGAP00000002004.2};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000002004.2, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000002004.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AAQR03022681; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03022682; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03022683; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 30611.ENSOGAP00000002004; -.
DR Ensembl; ENSOGAT00000002247.2; ENSOGAP00000002004.2; ENSOGAG00000002237.2.
DR eggNOG; KOG3544; Eukaryota.
DR GeneTree; ENSGT00940000154535; -.
DR HOGENOM; CLU_001074_2_1_1; -.
DR InParanoid; H0WKB9; -.
DR OMA; CDTPHKD; -.
DR TreeFam; TF323987; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0005592; C:collagen type XI trimer; IEA:Ensembl.
DR GO; GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProt.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005201; F:extracellular matrix structural constituent; IEA:InterPro.
DR GO; GO:0001502; P:cartilage condensation; IEA:Ensembl.
DR GO; GO:0002063; P:chondrocyte development; IEA:Ensembl.
DR GO; GO:0030199; P:collagen fibril organization; IEA:Ensembl.
DR GO; GO:0050910; P:detection of mechanical stimulus involved in sensory perception of sound; IEA:Ensembl.
DR GO; GO:0048704; P:embryonic skeletal system morphogenesis; IEA:Ensembl.
DR GO; GO:0035987; P:endodermal cell differentiation; IEA:Ensembl.
DR GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR GO; GO:0006029; P:proteoglycan metabolic process; IEA:Ensembl.
DR GO; GO:0035989; P:tendon development; IEA:Ensembl.
DR GO; GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IEA:Ensembl.
DR GO; GO:0007601; P:visual perception; IEA:Ensembl.
DR CDD; cd00110; LamG; 1.
DR Gene3D; 2.60.120.1000; -; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000885; Fib_collagen_C.
DR InterPro; IPR001791; Laminin_G.
DR InterPro; IPR048287; TSPN-like_N.
DR PANTHER; PTHR24023; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24023:SF42; COLLAGEN ALPHA-1(XI) CHAIN; 1.
DR Pfam; PF01410; COLFI; 1.
DR Pfam; PF01391; Collagen; 6.
DR Pfam; PF02210; Laminin_G_2; 1.
DR SMART; SM00038; COLFI; 1.
DR SMART; SM00282; LamG; 1.
DR SMART; SM00210; TSPN; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR PROSITE; PS51461; NC1_FIB; 1.
PE 4: Predicted;
KW Collagen {ECO:0000256|ARBA:ARBA00023119};
KW Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005225};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022530};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 16..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1582..1810
FT /note="Fibrillar collagen NC1"
FT /evidence="ECO:0000259|PROSITE:PS51461"
FT REGION 445..513
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 532..1551
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 453..489
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 685..719
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 777..791
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 912..948
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1131..1145
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1222..1236
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1296..1329
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1353..1368
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1498..1514
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1534..1550
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1811 AA; 181572 MW; 082604B80F01C5FF CRC64;
WTCFFRLLFC LKNGTVTAYF IIVTFFLFFT CFSAAPVDVL KALDFHNSPE GISKTTGFCT
NRKNSKGSDA AYRVSKQAQV SAPTKQLFPG GTFPEDFSIL FTVKPKKGIQ SFLLSIYNEH
GIQQVGVEVG RSPVFLFEDH TGKPAPEDYP LFRTVNIADG KWHRVAISVE KKTVTMIVDC
KKKTTKPLDR SERAIVDTNG ITVFGTRILD EEVFEGDIQQ LLITGDPKAA YDYCEHYSPD
CDSSAPKAAQ AQEPQIDEYA PEDLIEYDYE YGEAEYKEAE SVTEGPLVTE ETVAQTEANV
VDDFQEYNYG TMESYQTEAP RRVSGTNEEN PNPVEEVFTE EYLTGEDLTG EDYDSQRKNS
EDTLYENREI DGRDSDLLVD GDLGEYDFYE YKEYEDKPTS PTNEEFGPGV PAETDITETS
INGHGVYGEK GQKGEPAVVE PGMLVEGPPG PAGPAGLMGP PGLPGPTGPP GDPGDRGPPG
RPGLPGADGL PGPPGTMLML PFRYGGDGSK GPTISAQEAQ AQAILQQARI ALRGPPGPMG
LTGRPGPVGG PGSAGAKGES GDPGPQGPRG VQGPPGPTGK PGKRGRPGAD GGRGMPGEPG
SKGDRGFDGL PGLPGDKGHR GERGPQGPPG APGDDGMRGE DGEIGPRGLP GEAGPRGLLG
PRGTPGIPGQ PGMAGVDGPP GPKGNMGPQG EPGPPGQQGN PGPQGLPGPQ GPIGPPGEKG
PQGKPGLGGL PGADGPPGHP GKEGQSGEKG ALGPPGPQGP IGYPGPRGVK GADGVRGLKG
SKGEKGEDGF PGFKGDMGLK GDRGEVGQIG PRGEDGPEGP KGRAGPTGDL GPPGQAGEKG
KLGVPGLPGY PGRQGPKGST GFPGFPGANG EKGARGVAGK PGPRGQRGPT GPRGSRGARG
PTGKPGPKGT SGGDGPPGPP GERGPQGPQG PVGFPGPKGP PGPPGKDGLP GHPGQRGETG
FQGKTGPPGP GGVVGPQGPT GETGPIGERG HPGPPGPPGE QGLPGAAGKE GAKGDPGPQG
ISGKDGPAGL RGFPGERGLP GAQGAPGLKG GEGPQGPPGP VGSPGERGSA GTAGPIGLPG
RPGPQGPPGP AGEKGAPGEK GPQGPAGRDG VQGPVGLPGP AGPAGSPGED GDKGEIGEPG
QKGSKGDKGE NGPPGPPGLQ GPVGAPGIAG GDGEPGPRGQ QGMFGQKGDE GARGFPGPPG
PIGLQGLPGP PGEKGENGDV GPMGPPGPPG PRGPQGPNGA DGPQGPTGSV GSVGGVGEKG
EPGEAGNPGP PGEAGPGGPK GERGEKGEAG PPGAAGPPGA KGPPGDDGPK GNPGPVGFPG
DPGPPGEPGP SGQDGVSGDK GEDGDTGQPG PPGPSGEAGP PGPPGKRGPP GAAGAEGRQG
EKGAKGEAGA EGPSGKTGPV GPQGPAGKPG PEGLRGIPGP VGEQGLPGAA GQDGPPGPLG
PPGLPGLKGD PGSKGEKGHP GLIGLIGPPG EQGEKGDRGL PGTQGSPGAK GDGGIPGPAG
PIGPPGPPGL PGPQGPKGNK GSSGPAGQKG DSGLPGPPGP PGPPGEVIQP LPILSPKKTR
RHTESMQADA EDNIVDYWDG MEEIFGSLNS LKQDIEHMKF PMGTQTNPAR TCKDLQLSHP
DFPDGEYWID PNQGCTGDSF KVYCNFTSGG ETCIYPEKKS EGVRISSWPK ERPGSWYSEF
KRGKMLSYLD VEGNSINMVQ MTFLKLLTAS ARQNFTYNCH QSAAWYDVSS GSYDKALRFL
GSNDEEMSHD NNPFIKALYD GCASRKGYEK TVIEINTPKI DQVPIVDVMI NDFGDQNQKF
GFEVGPACFL G
//
