ID H0WKZ9_OTOGA Unreviewed; 1178 AA.
AC H0WKZ9;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Zinc finger CCCH-type containing 6 {ECO:0000313|Ensembl:ENSOGAP00000002285.2};
GN Name=ZC3H6 {ECO:0000313|Ensembl:ENSOGAP00000002285.2};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000002285.2, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000002285.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAQR03151697; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03151698; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03151699; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03151700; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03151701; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H0WKZ9; -.
DR STRING; 30611.ENSOGAP00000002285; -.
DR Ensembl; ENSOGAT00000002559.2; ENSOGAP00000002285.2; ENSOGAG00000002556.2.
DR eggNOG; KOG1040; Eukaryota.
DR GeneTree; ENSGT00940000157396; -.
DR HOGENOM; CLU_008238_0_0_1; -.
DR InParanoid; H0WKZ9; -.
DR OMA; RGMKQQQ; -.
DR TreeFam; TF321641; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.20.120.1350; Pneumovirus matrix protein 2 (M2), zinc-binding domain; 1.
DR Gene3D; 4.10.1000.10; Zinc finger, CCCH-type; 1.
DR InterPro; IPR045124; Su(sable)-like.
DR InterPro; IPR000571; Znf_CCCH.
DR InterPro; IPR036855; Znf_CCCH_sf.
DR PANTHER; PTHR13119; ZINC FINGER CCCH DOMAIN-CONTAINING PROTEI; 1.
DR PANTHER; PTHR13119:SF22; ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 6; 1.
DR Pfam; PF00642; zf-CCCH; 1.
DR Pfam; PF14608; zf-CCCH_2; 1.
DR Pfam; PF18345; zf_CCCH_4; 1.
DR SMART; SM00356; ZnF_C3H1; 3.
DR SUPFAM; SSF90229; CCCH zinc finger; 3.
DR PROSITE; PS50103; ZF_C3H1; 3.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00723}; Reference proteome {ECO:0000313|Proteomes:UP000005225};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00723};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00723}.
FT DOMAIN 263..289
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT DOMAIN 291..318
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT DOMAIN 319..342
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT ZN_FING 263..289
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT ZN_FING 291..318
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT ZN_FING 319..342
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT REGION 1..127
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 165..194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 441..570
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 623..650
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 666..686
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 711..765
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 798..819
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 943..1011
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1041..1113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1128..1178
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 339..374
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..21
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 35..61
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 74..94
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 165..181
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 446..483
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 491..516
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 623..640
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 666..685
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 711..729
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 732..765
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 801..819
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 968..1004
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1041..1067
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1079..1094
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1133..1152
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1153..1167
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1178 AA; 131164 MW; 31593651C70755CC CRC64;
REDGELEDGE IDDAGFEETQ EQEAKEDEKQ KNEKAYRKSR KKHKKEREKK KSKRRKREKH
KHNSPSSDDS SDYSLDSDIE HIESSHKKRT GFYRDYDIPF PQHGHISGSY MTSKKGQRNK
KYKSKEYDEY STYSDDNFGN YSDDNFGNYS QETEEDFASQ LKQYRQAKET SNTTLGSSFS
KEPGKKQRMK GLQQGIEQRV KSFNVSRGRG LLKKIKRKDR GGRSNKGPNV FSVTDDFQEY
SKPGKKWKVM TQEFINQHTV EHKGKQICKY FLEGRCIKGD QCKFDHDAEL EKRKEICKFY
LQGYCTKGEN CIYMHNEFPC KFYHSGAKCY QGDNCKFSHD DLTKETKKLL DKVLNADEEL
INEDERELEE LRKHGITPLP KPPPGVGLLP TPSEHFPFSD PEDDFQTDLS DDFKKIPSLF
EIVVKPTVDL AHKIGKKPPA FYNSASPPGP QFQGSSPHPQ HVYSSGSSPG PGPNTSQGRS
SPVMHPGSPG HHPCSGPPCL PVAQSPPLPP GPPEIVGPHN QAGVLVQPDT PLALPNMDGA
YQSPGFPGHM MKVPRENHGS PGSSYQQSPG EMQLNTTYES LQNPAEFYDN YYSQHTVHNF
QPPNTSGDGM WHGEFAQQQP PVLQDSLSCG SGSDASSSRT GHGPLPAPGL LPAVQRALFV
RLTQRYQEDE EQTSTQPHRI PQKHLDDTVN WYSSSEEEEG SSVKSILKTL QRQTESLRSQ
QQPSTELGTP TDPRLAKEKS KGNQVVDPRL RTVPRHDIKK PSEPAPLDLR LAWDPRKLRG
NGSSHIGSSV GGAKFDLHHT NAGTNAKHKR GDDDDEDTER ELREKAFIIP LDAPPGIMLQ
DPRSQLRQFS HIKMDIILTK PNFAKHIVWA PEDLLPVPLP KPDPVSSINL PLPPLIADQR
LNRLWNTKSD LHQNTVATDP KLAAKAKINT TNRETYLEQF GDLHSSGSKL GDPRLQKNFD
PRLHRQPNTE SHQVIIKDAH TSKATPQLAR SNPGSSQSLG PGASNSGPGA LPPYAPKLLS
SAGLPLGTSS SVLGGISLYD SRDHNSSSTS ELATVSLGEN AENQKKSISL KNSDKNEPSP
EETILPQKTT PNMEVTVDGP ADPQADLRSS GKVQVPAVHS LPIQALSGLI RPQYSDPRQS
RQPGQVSPTP DSDTSRETDD KSLKEVFKTF DPTASPFC
//
