ID H0WMP6_OTOGA Unreviewed; 846 AA.
AC H0WMP6;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=Bromo domain-containing protein {ECO:0000259|PROSITE:PS50014};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000003028.2, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000003028.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAQR03009422; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03009423; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03009424; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03009425; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03009426; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03009427; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03009428; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H0WMP6; -.
DR STRING; 30611.ENSOGAP00000003028; -.
DR Ensembl; ENSOGAT00000003397.2; ENSOGAP00000003028.2; ENSOGAG00000003386.2.
DR eggNOG; ENOG502QRPS; Eukaryota.
DR GeneTree; ENSGT00530000064262; -.
DR HOGENOM; CLU_007253_0_0_1; -.
DR InParanoid; H0WMP6; -.
DR OMA; NDDINHG; -.
DR TreeFam; TF106422; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR CDD; cd05507; Bromo_brd8_like; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR InterPro; IPR037966; Brd8_Bromo_dom.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR PANTHER; PTHR15398; BROMODOMAIN-CONTAINING PROTEIN 8; 1.
DR PANTHER; PTHR15398:SF4; BROMODOMAIN-CONTAINING PROTEIN 8; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000005225}.
FT DOMAIN 675..745
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 251..275
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 572..623
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 774..846
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 112..182
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 590..604
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 782..846
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 846 AA; 93701 MW; 165B51A75642AFCD CRC64;
KPARSVWNES TEFLKPPFLS EHKLLSTGPT EPWSIREKLC LASSVMRSGD QNWVSVSRAI
KPFAEPGRPP DWFSQKHCAS QYSELLETTE TPKRKRGEKG EVVETVEDVI VRKLTAERVE
ELKKVIKETQ ERYRRLKRDA ELIQAGHMDS RLDELCNDIA MKKKLEEEEA EVKRKATDAA
YQARQAVKTP PRRLPTVMVR SPIDSASPGG DYPLGDLTPT SIEEATSGGV LLEVGGVLPM
IHGGEIQQTP NTVAASPAAS AKVAGSNPQP GPAKTTMTAA KTLDIGICMM LICVVYSTLS
FSRKAISLQI SLIIISLIIT SGAPTLSRLL EAGPTQFTTP LASFTTVASE PPVKLVPPPP
ESMLSPSHGS NPIDDPLEAE TQHKFEMSGI MGCGQVEEVG QVSVERKGKA KVEKSSGSLS
LLCRLIERRI RDYFWKPDKG ISEFSLFLLP LLSFNKLTSL FSEMRLVRSW GQVRYSRSII
ATHASHLKKF VNITVLSLHT VHKEALTHKA HKAYTQILRI TKAVVTELKV IWCGAAPVAQ
RSRALTPYAG GDGFKPSPRT LYLGSEFLSR AREKKDAPGE DEEEDGVSEV ASLEEPKEED
QGEGYLSEMD NEPPVSESDD GFSIHNATLQ SHTLADSIPS SPASSQFSVC SEDQEAIQAQ
KIWKKAIMLV WRAAANHRYA NVFLQPVTDD IAPGYHSIVQ RPMDLSTIKK NIENGLIRST
AEFQRDIMLM FQNAVMYNSS DHDVYHMAVE MQRDVLEQIQ QFLATQLIMQ TSESGISAKS
LRGRDSTRKQ DASEKVRKPD SKVLHKRKEL GYRERAANGK KPSDCPDDGG TRGRRCAIEA
DMKMKK
//
