ID H0WP26_OTOGA Unreviewed; 1322 AA.
AC H0WP26;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Sperm associated antigen 9 {ECO:0000313|Ensembl:ENSOGAP00000003616.2};
GN Name=SPAG9 {ECO:0000313|Ensembl:ENSOGAP00000003616.2};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000003616.2, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000003616.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the JIP scaffold family.
CC {ECO:0000256|ARBA:ARBA00009866}.
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DR EMBL; AAQR03157866; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03157867; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03157868; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03157869; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03157870; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03157871; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03157872; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03157873; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03157874; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03157875; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 30611.ENSOGAP00000003616; -.
DR Ensembl; ENSOGAT00000004063.2; ENSOGAP00000003616.2; ENSOGAG00000004059.2.
DR eggNOG; KOG2077; Eukaryota.
DR GeneTree; ENSGT00940000153496; -.
DR HOGENOM; CLU_003841_0_0_1; -.
DR InParanoid; H0WP26; -.
DR OMA; MEYIERT; -.
DR TreeFam; TF313096; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0034451; C:centriolar satellite; IEA:Ensembl.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005765; C:lysosomal membrane; IEA:Ensembl.
DR GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR GO; GO:0008432; F:JUN kinase binding; IEA:Ensembl.
DR GO; GO:0019894; F:kinesin binding; IEA:Ensembl.
DR GO; GO:0005078; F:MAP-kinase scaffold activity; IEA:Ensembl.
DR GO; GO:0032418; P:lysosome localization; IEA:Ensembl.
DR GO; GO:0030335; P:positive regulation of cell migration; IEA:Ensembl.
DR GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR GO; GO:0042147; P:retrograde transport, endosome to Golgi; IEA:Ensembl.
DR GO; GO:0051146; P:striated muscle cell differentiation; IEA:Ensembl.
DR Gene3D; 1.20.58.1770; -; 1.
DR Gene3D; 1.20.5.1000; arf6 gtpase in complex with a specific effector, jip4; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR039911; JIP3/JIP4.
DR InterPro; IPR032486; JIP_LZII.
DR InterPro; IPR019143; JNK/Rab-associated_protein-1_N.
DR InterPro; IPR034743; RH1.
DR InterPro; IPR034744; RH2.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR13886:SF2; C-JUN-AMINO-TERMINAL KINASE-INTERACTING PROTEIN 4; 1.
DR PANTHER; PTHR13886; JNK/SAPK-ASSOCIATED PROTEIN; 1.
DR Pfam; PF16471; JIP_LZII; 1.
DR Pfam; PF09744; Jnk-SapK_ap_N; 1.
DR Pfam; PF19056; WD40_2; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS51776; RH1; 1.
DR PROSITE; PS51777; RH2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000005225}.
FT DOMAIN 7..95
FT /note="RH1"
FT /evidence="ECO:0000259|PROSITE:PS51776"
FT DOMAIN 500..604
FT /note="RH2"
FT /evidence="ECO:0000259|PROSITE:PS51777"
FT REGION 182..306
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 473..500
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 563..599
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 855..904
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1241..1270
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 75..162
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 728..755
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 222..251
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 265..289
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 579..599
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1322 AA; 146296 MW; 7FD73A6DA73AB8F9 CRC64;
MELEDGVVYQ EEPGGSGAVM SERVSGLAGS IYREFERLIG RYDEEVVKEL MPLVVAVLEN
LDSVFAQDQE HQVELELLRD DNEQLITQYE REKALRKHAE EKFIEFEDSQ EQEKKDLQTR
VESLESQTRQ LELKAKNYAD QISRLEEREA ELKKEYNALH QRHTEMIHNY MEHLERTKLH
QLSGSDQLES TAHSRIRKER PISLGIFPLP AGDGLLTPDT QKGGETPGSE QWKFQELSQP
RSHTSLKVSN SPEPVKAVEQ EDELSDVSQG GSKATTPAST ANSDVATIPT DTPLKEDNEG
FVKVTDTPNK SEISKHIEVQ VAQETRNVST GNAENEEKSE VQAIIESTPE LDMDKDLSGY
KGSSTPTKGI ENKAFDRNTE SLFEELSSAG SGLIGDVDEG ADLLGMGREV ENLILENTQL
LETKNALNVV KNDLIAKVDE LTCEKDVLQG ELEAVKQAKL KLEEKNRELE EELRRARAEA
EDARQKAKDD DDSDIPTAQR KRFTRVEMAR VLMERNQYKE RLMELQEAVR WTEMIRASRE
NPAMQEKKRS SIWQFFSRLF SSSSNTAKKP EPPVNLKYNA PTSHVTPSVK KRSSTLSQLP
GDKSKAFDFL SEETEASLAL RREQKREQYR QVKAHVQKED GRVQAFGWSL PQKYKQVTNG
QGENKMKNLP VPVYLRPLDE KDTSMKKLWC AVGVNLSGGK TRDGGSVIGA SVFYKDVAGL
DTESSKQRSA SQSSLDKLDQ ELKEQQKELK NQEELSSLVW ICTSTHSATK VIIIDAVQPG
NILDSFTVCN SHILCIASVP GARETDYPAG EDLLESGQVD KASLCGSMTS NSSAETDSLL
GGITVVGCSA EGVTGAATSP STNGASPVIE KPPETEPESS EVDENVPTAE EATEATEGNA
GSAEDTIDIS QAGVYTEHVF TDPLGVQIPE DLSPVYQSSN DADAYKDQVS VLPSEQDLVR
EEAQKMSSLL PTMWLGAQNG CLYVHSSVAQ WRKCLHSIKL KDSILSIVHV KGIVLVALAD
GTLAIFHRGV DGQWDLSNYH LLDLGRPHHS IRCMTVVHDK VWCGYRNKIY VVQPKAMKIE
KSFDAHPRKE SQVRQLAWVG DGVWVSIRLD STLRLYHAHT YQHLQDVDIE PYVSKMLGTG
KLGFSFVRIT ALMVSCNRLW VGTGNGVIIS IPLTETNKTS GAPGNRPGSV IRVYGDENSD
KVTPGTFIPY CSMAHAQLCF HGHRDAVKFF VAVPGQVVSP QSGNSGTDLT GDKAGPSTQE
PGSQTPSKSM LVISGGEGYI DFRMGDEGGE SELLGEDLPL EPSVTKAERS HLIVWQVMYG
SE
//
