ID   H0WPS7_OTOGA            Unreviewed;       610 AA.
AC   H0WPS7;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   27-MAR-2024, entry version 47.
DE   SubName: Full=Methyltransferase like 25 {ECO:0000313|Ensembl:ENSOGAP00000003916.2};
GN   Name=METTL25 {ECO:0000313|Ensembl:ENSOGAP00000003916.2};
OS   Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC   Galagidae; Otolemur.
OX   NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000003916.2, ECO:0000313|Proteomes:UP000005225};
RN   [1] {ECO:0000313|Proteomes:UP000005225}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   The Broad Institute Genome Sequencing Platform;
RA   Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA   Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA   Walker B.J., Sharpe T., Hall G.;
RT   "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL   Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSOGAP00000003916.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AAQR03017113; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03017114; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03017115; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03017116; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03017117; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03017118; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03017119; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03017120; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; H0WPS7; -.
DR   STRING; 30611.ENSOGAP00000003916; -.
DR   Ensembl; ENSOGAT00000004388.2; ENSOGAP00000003916.2; ENSOGAG00000004384.2.
DR   eggNOG; KOG2651; Eukaryota.
DR   GeneTree; ENSGT00530000063745; -.
DR   HOGENOM; CLU_016581_2_0_1; -.
DR   InParanoid; H0WPS7; -.
DR   OMA; CCYHLLR; -.
DR   TreeFam; TF312998; -.
DR   Proteomes; UP000005225; Unassembled WGS sequence.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR025714; Methyltranfer_dom.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR12496; CGI-41 METHYLTRANSFERASE; 1.
DR   PANTHER; PTHR12496:SF9; METHYLTRANSFERASE-LIKE PROTEIN 25-RELATED; 1.
DR   Pfam; PF13679; Methyltransf_32; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000005225}.
FT   DOMAIN          154..425
FT                   /note="Methyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF13679"
SQ   SEQUENCE   610 AA;  68765 MW;  D7EC6D8876205F5B CRC64;
     MAACGPLPVT PDLPTLRAKL QGLLGFLRDA LSISNAHTVD FYTESVWEEL VDLPPETVLT
     VLRRSAAETE ARPSESRPLV EAEKGSGMAN LPKIFCETSQ KLVNVEAFAL AAKYYSVQNM
     GICTPFEQLL VALQGNEKQR SGETVRPVEF MNMKKSHEVQ AMSELISSIA AYYGVKQVID
     LGSGKGYLSS FLSLKYGLKV YGIDSSNTNT HGAEKRNRKL KKHWKLCHAQ PRLDVSRLAL
     KVSKEKKVQN EIKYKADIEK VHNSSLPKQE EMSTSIFLPD LSGSVISAVR KQMEKHKQME
     NLHALPQQEE NLCFENTSSL IDLLPLNAIE SAALLQMPNR EVSETNQERR KITSKSSESN
     IYSPLTSFIT ADSELHDIIK DLEDCLMVGL HTCGDLAPNT LRIFTSKSEI KGVCSVGCCY
     HLLSEEFETQ TTECTQEKWG FPMCHYLKEE KWCCGRNARM SACLVCHSPS LAAKSLPTES
     LFYRAVLQDI IKDCYGITKC DQHVGKIYSK CSSFLDYVRK SLVKLQLDES KLPEKLIMNY
     YEMYKPRMNE LEAFNMLKVV LAPCIETLIL LDRLCYLKEQ EDIAWSALVK LFDPVKSPRC
     YAVIALKKQQ
//