ID H0WQZ5_OTOGA Unreviewed; 419 AA.
AC H0WQZ5;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Jumonji domain containing 4 {ECO:0000313|Ensembl:ENSOGAP00000004413.2};
GN Name=JMJD4 {ECO:0000313|Ensembl:ENSOGAP00000004413.2};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000004413.2, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000004413.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=2-oxoglutarate + L-lysyl-[protein] + O2 = 4-hydroxy-L-lysyl-
CC [protein] + CO2 + succinate; Xref=Rhea:RHEA:57156, Rhea:RHEA-
CC COMP:9752, Rhea:RHEA-COMP:15084, ChEBI:CHEBI:15379,
CC ChEBI:CHEBI:16526, ChEBI:CHEBI:16810, ChEBI:CHEBI:29969,
CC ChEBI:CHEBI:30031, ChEBI:CHEBI:141495;
CC Evidence={ECO:0000256|ARBA:ARBA00035905};
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DR EMBL; AAQR03184001; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003803255.1; XM_003803207.2.
DR AlphaFoldDB; H0WQZ5; -.
DR STRING; 30611.ENSOGAP00000004413; -.
DR Ensembl; ENSOGAT00000004945.2; ENSOGAP00000004413.2; ENSOGAG00000004942.2.
DR GeneID; 100963172; -.
DR KEGG; oga:100963172; -.
DR CTD; 65094; -.
DR eggNOG; KOG2131; Eukaryota.
DR GeneTree; ENSGT00940000159380; -.
DR HOGENOM; CLU_016785_2_2_1; -.
DR InParanoid; H0WQZ5; -.
DR OMA; MFSRRFT; -.
DR OrthoDB; 120564at2759; -.
DR TreeFam; TF105936; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR Gene3D; 2.60.120.650; Cupin; 1.
DR InterPro; IPR041667; Cupin_8.
DR InterPro; IPR003347; JmjC_dom.
DR PANTHER; PTHR12480:SF6; 2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE JMJD4; 1.
DR PANTHER; PTHR12480; ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD; 1.
DR Pfam; PF13621; Cupin_8; 1.
DR SMART; SM00558; JmjC; 1.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR PROSITE; PS51184; JMJC; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005225}.
FT DOMAIN 142..301
FT /note="JmjC"
FT /evidence="ECO:0000259|PROSITE:PS51184"
SQ SEQUENCE 419 AA; 48061 MW; 54E28AE5E7E69C01 CRC64;
MDRETRALAE RYFRGGGRGD PRCSPVLGRV AFIPEPASFS YADFVRGFLL PNLPCVFSSA
FTEGWGGRRL WVTPTGRPDF DHLLRVYGDV VVPVANCGVQ EYNSNPKEHM PLRDYITYWK
EYIQGGYSSP RGCLYLKDWH LCRDSSAEDV FTLPVYFSSD WLNEFWDALD VDDYRFVYAG
PKGTWSPFHA DIFRSFSWSV NICGRKKWLL FPPGQEEALR DRHGSLPYDV TSPLLLDAHQ
YPRRQHCGPP LEVTQEAGEM LFVPSGWHHQ VHNLDDTISI NHNWVNGFNL AHMWHFLQQE
LRAVQEEIGE WRDSMPNWNH HCQVIMRSCS GINFEEFYHF LKVIAERRLL VLGKGMAEGS
AGAELGPEQA AFDVGRISEV LASVVEHPDF QRVDTSMFSP QPEELLQQLR EAVGVTMVL
//
