ID H0WSQ9_OTOGA Unreviewed; 213 AA.
AC H0WSQ9;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=Motile sperm domain-containing protein 1 {ECO:0000256|ARBA:ARBA00020941};
GN Name=MOSPD1 {ECO:0000313|Ensembl:ENSOGAP00000005131.2};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000005131.2, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000005131.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}. Golgi apparatus membrane
CC {ECO:0000256|ARBA:ARBA00004653}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004653}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AAQR03131477; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03131478; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03131479; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03131480; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03131481; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003797016.1; XM_003796968.2.
DR AlphaFoldDB; H0WSQ9; -.
DR STRING; 30611.ENSOGAP00000005131; -.
DR Ensembl; ENSOGAT00000005741.2; ENSOGAP00000005131.2; ENSOGAG00000005739.2.
DR GeneID; 100951276; -.
DR KEGG; oga:100951276; -.
DR CTD; 56180; -.
DR eggNOG; KOG0439; Eukaryota.
DR GeneTree; ENSGT00940000155266; -.
DR HOGENOM; CLU_088040_0_0_1; -.
DR InParanoid; H0WSQ9; -.
DR OMA; NARHTHK; -.
DR OrthoDB; 4837153at2759; -.
DR TreeFam; TF319778; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR039283; MOSPD1/3.
DR InterPro; IPR000535; MSP_dom.
DR InterPro; IPR008962; PapD-like_sf.
DR PANTHER; PTHR34441; MOTILE SPERM DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR34441:SF2; MOTILE SPERM DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00635; Motile_Sperm; 1.
DR SUPFAM; SSF49354; PapD-like; 1.
DR PROSITE; PS50202; MSP; 1.
PE 4: Predicted;
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005225};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 160..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 191..211
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 16..143
FT /note="MSP"
FT /evidence="ECO:0000259|PROSITE:PS50202"
SQ SEQUENCE 213 AA; 24059 MW; D66DD2593F55007D CRC64;
MHQQKRQPEL VEGNLPVFVF PTELIFYADD QSTHKQVLTL YNPYEFALKF KVLCTTPNKY
VVVDAAGAVK PQCCVDIVIR HRDVRSCHYG VVDKFRLQVS EQSQRKALGR KEVVATLLPS
AKEQQKEEEE KRIKEHLSES LFFEQPFQPE NRAVSSGPSL LTVFLGVVCI AALMLPTLGD
VESLVPLYLQ LSVNQKLVAA YILGLITMAI LRT
//
