ID H0WTZ6_OTOGA Unreviewed; 221 AA.
AC H0WTZ6;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Tumor protein p53 inducible nuclear protein 2 {ECO:0000313|Ensembl:ENSOGAP00000005659.2};
GN Name=TP53INP2 {ECO:0000313|Ensembl:ENSOGAP00000005659.2};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000005659.2, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000005659.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, autophagosome
CC {ECO:0000256|ARBA:ARBA00004419}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; AAQR03054316; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H0WTZ6; -.
DR STRING; 30611.ENSOGAP00000005659; -.
DR Ensembl; ENSOGAT00000006336.2; ENSOGAP00000005659.2; ENSOGAG00000006332.2.
DR eggNOG; ENOG502RZHB; Eukaryota.
DR GeneTree; ENSGT00530000063829; -.
DR HOGENOM; CLU_091034_0_0_1; -.
DR InParanoid; H0WTZ6; -.
DR OMA; HQGSFIY; -.
DR TreeFam; TF333017; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0005776; C:autophagosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0043130; F:ubiquitin binding; IEA:Ensembl.
DR GO; GO:0000045; P:autophagosome assembly; IEA:Ensembl.
DR GO; GO:1903828; P:negative regulation of protein localization; IEA:Ensembl.
DR GO; GO:0001649; P:osteoblast differentiation; IEA:Ensembl.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:Ensembl.
DR GO; GO:0008104; P:protein localization; IEA:Ensembl.
DR GO; GO:0001894; P:tissue homeostasis; IEA:Ensembl.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR InterPro; IPR029431; TP53INP.
DR PANTHER; PTHR31671; DIABETES AND OBESITY REGULATED, ISOFORM G; 1.
DR PANTHER; PTHR31671:SF2; TUMOR PROTEIN P53-INDUCIBLE NUCLEAR PROTEIN 2; 1.
DR Pfam; PF14839; DOR; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000005225};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 175..213
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 175..197
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 221 AA; 24376 MW; 82BDF4387C21A743 CRC64;
MFQRLTSLFF STPPSPEDPD CSHAFVSEED EVDGWLIIDL PDSYAAPPNP RAAPAPAGRP
PPAPSLMDES WFVTPPACFT AEGPGLGPTR LQSSPLEDLL IEHPSMSVYV TGSTIVLEPG
PPSPHSDAAL PDGDLSDLEL APARREPRAL RHAAAPLPAR AVLLEKAGQM RRLQRARQRA
ERHALSAKVV QRQNRARESR PRRPKHQGSF VYQPCRRQFN Y
//
