ID H0WUF9_OTOGA Unreviewed; 533 AA.
AC H0WUF9;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Interleukin 20 receptor subunit alpha {ECO:0000313|Ensembl:ENSOGAP00000005860.2};
GN Name=IL20RA {ECO:0000313|Ensembl:ENSOGAP00000005860.2};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000005860.2, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000005860.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAQR03075746; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H0WUF9; -.
DR STRING; 30611.ENSOGAP00000005860; -.
DR Ensembl; ENSOGAT00000006556.2; ENSOGAP00000005860.2; ENSOGAG00000006549.2.
DR eggNOG; ENOG502RPFC; Eukaryota.
DR GeneTree; ENSGT00940000157314; -.
DR HOGENOM; CLU_527430_0_0_1; -.
DR InParanoid; H0WUF9; -.
DR OMA; MINFITL; -.
DR TreeFam; TF334107; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0042015; F:interleukin-20 binding; IEA:Ensembl.
DR GO; GO:0019221; P:cytokine-mediated signaling pathway; IEA:Ensembl.
DR GO; GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; IEA:Ensembl.
DR GO; GO:0045124; P:regulation of bone resorption; IEA:Ensembl.
DR CDD; cd00063; FN3; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR015373; Interferon/interleukin_rcp_dom.
DR PANTHER; PTHR20859; INTERFERON/INTERLEUKIN RECEPTOR; 1.
DR PANTHER; PTHR20859:SF86; INTERLEUKIN-20 RECEPTOR SUBUNIT ALPHA; 1.
DR Pfam; PF09294; Interfer-bind; 1.
DR Pfam; PF01108; Tissue_fac; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR PROSITE; PS50853; FN3; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005225};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 235..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 22..118
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 119..225
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 317..340
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 358..385
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 440..465
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 360..374
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 533 AA; 60925 MW; B5E96FC48E5F675F CRC64;
PLRLPFLSTP LSVPCVSGGL PKPTNITFLS INMKNVLQWN PPEGLQGVEV TYTVQYFIYG
QKRWLNKSEC RNINRTYCDL SVETSDYEHQ YYAKVKAIWE TNCSKWAETG RFYPFVETQI
GPPEVALTTD EKSMSIFLTP PEKWKRNPED SSVSMQQIYS NLKYNVSIRN TRSNRMWSQC
VTNHTLVLTW LEPDTQYCVH VEAFVPGLPR PTRPSEKQCV RTLKDPSSEF KVKIIFWYVL
PISIMVFLFS VMGYSIYRYI HVGKERHPAN LILIYGNEFD KRFFVPAEKI VINFISLSIL
DDSKNSQKDT GLLEKSISDV SDLNNPEPSR NPEPPQGEEE VKHLGYASHL VEILCDSEEN
TKGASRSQQE ASSRTTSTEK RDLGYEYDVR SADSCAGPED PALSLQQVSG RGSLYEHRAA
LAQLDPPMSL YSRAPQLRDL HSQAQEHTDS EEGPEEEPSA TLVDWDPRTG RLCLSSLSSY
DQDSEHAEND RLAEEGLLAR LYEAQAPDKP PEEHETYLLQ FMEEWGLYVQ MEN
//
