GenomeNet

Database: UniProt
Entry: H0WUI3_OTOGA
LinkDB: H0WUI3_OTOGA
Original site: H0WUI3_OTOGA 
ID   H0WUI3_OTOGA            Unreviewed;       719 AA.
AC   H0WUI3;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   20-JUN-2018, entry version 41.
DE   SubName: Full=Transglutaminase 2 {ECO:0000313|Ensembl:ENSOGAP00000005896};
GN   Name=TGM2 {ECO:0000313|Ensembl:ENSOGAP00000005896};
OS   Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini;
OC   Lorisiformes; Galagidae; Otolemur.
OX   NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000005896, ECO:0000313|Proteomes:UP000005225};
RN   [1] {ECO:0000313|Ensembl:ENSOGAP00000005896}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   The Broad Institute Genome Sequencing Platform;
RA   Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA   Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA   Walker B.J., Sharpe T., Hall G.;
RT   "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL   Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSOGAP00000005896}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JAN-2012) to UniProtKB.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AAQR03049920; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03049921; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03049922; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 30611.ENSOGAP00000005896; -.
DR   Ensembl; ENSOGAT00000006596; ENSOGAP00000005896; ENSOGAG00000006593.
DR   eggNOG; ENOG410IFMV; Eukaryota.
DR   eggNOG; ENOG410XQEZ; LUCA.
DR   GeneTree; ENSGT00760000119108; -.
DR   InParanoid; H0WUI3; -.
DR   OMA; AHITNNT; -.
DR   OrthoDB; EOG091G030K; -.
DR   TreeFam; TF324278; -.
DR   Proteomes; UP000005225; Unassembled WGS sequence.
DR   GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:GOC.
DR   GO; GO:0031226; C:intrinsic component of plasma membrane; IEA:Ensembl.
DR   GO; GO:0005739; C:mitochondrion; IEA:Ensembl.
DR   GO; GO:0003810; F:protein-glutamine gamma-glutamyltransferase activity; IEA:Ensembl.
DR   GO; GO:0043277; P:apoptotic cell clearance; IEA:Ensembl.
DR   GO; GO:0060445; P:branching involved in salivary gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0032471; P:negative regulation of endoplasmic reticulum calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0018149; P:peptide cross-linking; IEA:InterPro.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0045785; P:positive regulation of cell adhesion; IEA:Ensembl.
DR   GO; GO:0051561; P:positive regulation of mitochondrial calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0060662; P:salivary gland cavitation; IEA:Ensembl.
DR   Gene3D; 2.60.40.10; -; 3.
DR   Gene3D; 3.90.260.10; -; 1.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR038765; Papain_like_cys_pep_sf.
DR   InterPro; IPR002931; Transglutaminase-like.
DR   InterPro; IPR036985; Transglutaminase-like_sf.
DR   InterPro; IPR023608; Transglutaminase_animal.
DR   InterPro; IPR013808; Transglutaminase_AS.
DR   InterPro; IPR008958; Transglutaminase_C.
DR   InterPro; IPR036238; Transglutaminase_C_sf.
DR   InterPro; IPR001102; Transglutaminase_N.
DR   Pfam; PF00927; Transglut_C; 1.
DR   Pfam; PF01841; Transglut_core; 1.
DR   Pfam; PF00868; Transglut_N; 1.
DR   PIRSF; PIRSF000459; TGM_EBP42; 1.
DR   SMART; SM00460; TGc; 1.
DR   SUPFAM; SSF49309; SSF49309; 2.
DR   SUPFAM; SSF54001; SSF54001; 1.
DR   SUPFAM; SSF81296; SSF81296; 1.
DR   PROSITE; PS00547; TRANSGLUTAMINASES; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005225};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005225}.
FT   DOMAIN      278    370       TGc. {ECO:0000259|SMART:SM00460}.
FT   ACT_SITE    286    286       {ECO:0000256|PIRSR:PIRSR000459-1}.
FT   ACT_SITE    344    344       {ECO:0000256|PIRSR:PIRSR000459-1}.
FT   ACT_SITE    367    367       {ECO:0000256|PIRSR:PIRSR000459-1}.
SQ   SEQUENCE   719 AA;  80673 MW;  631F0B8DCBE3A9D0 CRC64;
     LAHVSPTVST ELLMQKCDLE LETNDRDHHT AELCRERLVV RRGQPFQLKL HFNRKYNASQ
     DTLTFTVVTG PAPSQELGTK ARFSLSEALE ETAWSASVVN QDSALSLKIN SPANAPIGLY
     RLTLEISSSE GSGLVGSSHT LGHFTLLFNA WCPADSVYLE LEEERQEYVL TQQGFIYQGS
     AKFIKTVPWN FGQFEDSILD TSLMLLDVNP KFVKNASRDC CRRSSPVYVC RVVSNMVNSN
     DDQGVLQGRW DNKYEDGISP MFWIGSADIL RRWKNNGCQP VKYGQCWVFA AVACTVLRCL
     GIPTRVVTNY NSAHDQNSNL LIEYVRNEMG ELQTDKSEMI WNFHCWVESW MTRPDLQPDY
     KGWQALDPTP QEKSEGTYCC GPVPVRAIKE GDLKAKYDAP FVFAEVNAEV INWIQKKDGS
     MHKSTNNSLV VGLHISTKGV GRDNRQDITH EYKYPEGSSE ERDVFTKANH INKLSGMRGT
     EGPGAGRTRP WSSRAAVRAS GTSLGSVAMS PESSVPFRFE CALASSPHAQ NHSKRRKCLS
     WNVWELVVRF HSAPPGPDLL IFTPFVLFGT EEKSIPLRIL YEKYADYMTD SNLIKVRALL
     VEQASNRYLL AERDLYLETP EIKIRILGEP KQNRKLVAEV SLRNPLNVSL MGCSFTVEGA
     GLIEEQKTVE LPNPVGPGEE AKTRVDLLPS QVGLYKLVVN FESDKLRAVK GYRNVIVGP
//
DBGET integrated database retrieval system