ID H0WVQ1_OTOGA Unreviewed; 179 AA.
AC H0WVQ1;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=CKLF like MARVEL transmembrane domain containing 3 {ECO:0000313|Ensembl:ENSOGAP00000006399.2};
GN Name=CMTM3 {ECO:0000313|Ensembl:ENSOGAP00000006399.2};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000006399.2, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000006399.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AAQR03153179; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03153180; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03153181; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H0WVQ1; -.
DR STRING; 30611.ENSOGAP00000006399; -.
DR Ensembl; ENSOGAT00000007145.2; ENSOGAP00000006399.2; ENSOGAG00000007144.2.
DR eggNOG; KOG4788; Eukaryota.
DR GeneTree; ENSGT00940000160432; -.
DR HOGENOM; CLU_108546_1_0_1; -.
DR InParanoid; H0WVQ1; -.
DR OMA; PLIEFLW; -.
DR TreeFam; TF317387; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0031410; C:cytoplasmic vesicle; IEA:Ensembl.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0031965; C:nuclear membrane; IEA:Ensembl.
DR GO; GO:0001835; P:blastocyst hatching; IEA:Ensembl.
DR GO; GO:0050861; P:positive regulation of B cell receptor signaling pathway; IEA:Ensembl.
DR InterPro; IPR008253; Marvel.
DR PANTHER; PTHR22776:SF3; CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 3; 1.
DR PANTHER; PTHR22776; MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN; 1.
DR Pfam; PF01284; MARVEL; 1.
DR PROSITE; PS51225; MARVEL; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|PROSITE-ProRule:PRU00581, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005225};
KW Transmembrane {ECO:0000256|PROSITE-ProRule:PRU00581,
KW ECO:0000256|SAM:Phobius}; Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 47..80
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 100..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 128..148
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 33..152
FT /note="MARVEL"
FT /evidence="ECO:0000259|PROSITE:PS51225"
SQ SEQUENCE 179 AA; 19369 MW; A5F0A47B79AB94CE CRC64;
LWPAPGESCP LSHPSQAGPA VPGLRALLPA RAFLCSLKGR LLLAESILSF ITFICYVASS
ASAFLTAPLL EFLLALYFLF ADAMQLNDKW QGLCWPMMDF LRCVTAALIY FAISITAVAK
YSDGASKAAG VFGFFATIVF AINFYLIFND VAKFLKQGNS AEETTAHKAE EESSDSDSD
//
