ID H0WWE8_OTOGA Unreviewed; 461 AA.
AC H0WWE8;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=Butyrophilin like 8 {ECO:0008006|Google:ProtNLM};
GN Name=LOC100959595 {ECO:0000313|Ensembl:ENSOGAP00000006703.2};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000006703.2, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000006703.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily. BTN/MOG family.
CC {ECO:0000256|ARBA:ARBA00007591}.
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DR EMBL; AAQR03161042; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03161043; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03161044; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03161045; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H0WWE8; -.
DR STRING; 30611.ENSOGAP00000006703; -.
DR Ensembl; ENSOGAT00000007499.2; ENSOGAP00000006703.2; ENSOGAG00000007497.2.
DR eggNOG; KOG2177; Eukaryota.
DR GeneTree; ENSGT00940000163611; -.
DR HOGENOM; CLU_013137_22_0_1; -.
DR InParanoid; H0WWE8; -.
DR OMA; FIMMAIF; -.
DR TreeFam; TF331083; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd05713; IgV_MOG_like; 1.
DR CDD; cd13733; SPRY_PRY_C-I_1; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR003877; SPRY_dom.
DR PANTHER; PTHR24100; BUTYROPHILIN; 1.
DR PANTHER; PTHR24100:SF140; BUTYROPHILIN-LIKE PROTEIN 3; 1.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF07686; V-set; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00409; IG; 1.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005225};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..461
FT /note="Butyrophilin like 8"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003544060"
FT TRANSMEM 233..258
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 138..218
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 270..461
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
SQ SEQUENCE 461 AA; 52208 MW; C2F2F1CE4DECF6F9 CRC64;
MVLVLALALS LLKLGSGQWQ VIGPNKPVQA LVGEDVVFSC FLSPETNAEA MEVRIFRDQF
SAIIHLYQDG KDQDYMQKPS YRGRTELMKD FIADGHVSLR LKKVTALDAG LYGCWFSSQT
YDQGTTWELQ VSEMGSAPLI SLTGFVDGGI RLLCQSSGWF SQPTVKWKGP QGHDIPSDSK
VNVDRHGLFD VETSLTLQEN LGSISCSVQL TDQSPEVTSS IWLGEMFFQR SPWLLAFISL
TPLCIGISVG IIGMKILFSK SQGKIQKKLE WRKKHRQADL KEVRKYAVEV TLDPDTAHPQ
LHVADLKTVC YTNVPQEVPH SEKRFTRMCV VASQGFQAGK HYWEVGVRHN KRWHLGVCRD
DVDRTRNNVI LSPDNGYWVL GLEMDWHFTL NPHRINLSLR NTLLQVGVFL DYEGGTISFF
NINDQSPIYT MTHRFEGLLR PYIQHEAYED ENVTPIVICP V
//
