ID H0WWP9_OTOGA Unreviewed; 609 AA.
AC H0WWP9;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Docking protein 7 {ECO:0000313|Ensembl:ENSOGAP00000006822.2};
GN Name=DOK7 {ECO:0000313|Ensembl:ENSOGAP00000006822.2};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000006822.2, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000006822.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAQR03169649; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03169650; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03169651; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03169652; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H0WWP9; -.
DR STRING; 30611.ENSOGAP00000006822; -.
DR Ensembl; ENSOGAT00000007627.2; ENSOGAP00000006822.2; ENSOGAG00000007622.2.
DR eggNOG; ENOG502QQBI; Eukaryota.
DR GeneTree; ENSGT00390000015386; -.
DR HOGENOM; CLU_024931_0_0_1; -.
DR InParanoid; H0WWP9; -.
DR OMA; AIICRSQ; -.
DR TreeFam; TF332288; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0005739; C:mitochondrion; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0019901; F:protein kinase binding; IEA:Ensembl.
DR CDD; cd14677; PH_DOK7; 1.
DR CDD; cd13165; PTB_DOK7; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR InterPro; IPR037746; Dok-7.
DR InterPro; IPR037747; Dok-7_PH.
DR InterPro; IPR037748; Dok-7_PTB.
DR InterPro; IPR002404; IRS_PTB.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR21636; PROTEIN DOK-7; 1.
DR PANTHER; PTHR21636:SF2; PROTEIN DOK-7; 1.
DR Pfam; PF02174; IRS; 1.
DR SMART; SM01244; IRS; 1.
DR SUPFAM; SSF50729; PH domain-like; 2.
DR PROSITE; PS51064; IRS_PTB; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005225}.
FT DOMAIN 4..109
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 105..210
FT /note="IRS-type PTB"
FT /evidence="ECO:0000259|PROSITE:PS51064"
FT REGION 210..230
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 247..349
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 371..491
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 509..532
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 584..609
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 258..300
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 328..349
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 588..609
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 609 AA; 63844 MW; 055BAB5F35BEE3D1 CRC64;
MTEAALVEGQ VKLRDGKKWK SRWLVLRKPS PVADCLLMLA YKDKSERAKG LRERSSLTLE
DICGLEPGLP YEGLPHTLAI VCLSQAVMLG FDSREVMCAW DARIRYALGE VHRFHVTVAP
GTKLESGPAT LHLCNDVLVL ARDIPPAVTG QWKLSDLRRY GAVPNGFIFE GGTRCGYWAG
VFFLSSAEGE QISFLFDCIV RGISPTKGPF GLRPVLPDPS PGGPSAVEER VTQEALEALQ
LDKRLSLLAP SGRPGSAGDD RSLSSSSSEA SHSDISASSR LTAWPEQSSS SASTSQEGPG
LAAAQVPGEA TLGASRPPPK PLRPRQLQEV GRQSSSDSGI ATGSHSSYSG SFSSYAGSSL
DVWRAGDEFG SLLSLPPAAG AVEPSLCACP PGAAEYQVPA GLRPHYDTPR SLRQAPRDQS
PASQGGPDDA VAGDSGGQTS TGCPSGWLGA RRRGQATEAP PGSGAMLPSP ASGEPWGASG
PHAGPSPAFF SPCPVCGGLK SSASAWALTA PLPTGSPRPG NTGSPGLERP SRELATYVNI
PISPSSRQQL HYLGLELQEA SPGVRGASTS RYTQINITAT QAAHRVGAQH AQDREEQLSE
LEQRKGAPQ
//
