ID H0WWU0_OTOGA Unreviewed; 109 AA.
AC H0WWU0;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=Parvalbumin {ECO:0000256|RuleBase:RU368048};
GN Name=OCM {ECO:0000313|Ensembl:ENSOGAP00000006868.2};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000006868.2, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000006868.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: In muscle, parvalbumin is thought to be involved in
CC relaxation after contraction. It binds two calcium ions.
CC {ECO:0000256|RuleBase:RU368048}.
CC -!- SIMILARITY: Belongs to the parvalbumin family.
CC {ECO:0000256|ARBA:ARBA00009753, ECO:0000256|RuleBase:RU368048}.
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DR EMBL; AAQR03148892; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003798943.1; XM_003798895.2.
DR AlphaFoldDB; H0WWU0; -.
DR SMR; H0WWU0; -.
DR STRING; 30611.ENSOGAP00000006868; -.
DR Ensembl; ENSOGAT00000007677.2; ENSOGAP00000006868.2; ENSOGAG00000007674.2.
DR GeneID; 100957471; -.
DR KEGG; oga:100957471; -.
DR CTD; 654231; -.
DR eggNOG; KOG0027; Eukaryota.
DR GeneTree; ENSGT00940000161875; -.
DR HOGENOM; CLU_157356_0_0_1; -.
DR InParanoid; H0WWU0; -.
DR OMA; KKFFQVC; -.
DR OrthoDB; 3531838at2759; -.
DR TreeFam; TF332342; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR CDD; cd16255; EFh_parvalbumin_beta; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR008080; Parvalbumin.
DR PANTHER; PTHR11653:SF4; ONCOMODULIN-2-RELATED; 1.
DR PANTHER; PTHR11653; PARVALBUMIN ALPHA; 1.
DR Pfam; PF13499; EF-hand_7; 1.
DR PRINTS; PR01697; PARVALBUMIN.
DR SMART; SM00054; EFh; 2.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS00018; EF_HAND_1; 2.
DR PROSITE; PS50222; EF_HAND_2; 2.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|RuleBase:RU368048};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU368048};
KW Reference proteome {ECO:0000313|Proteomes:UP000005225}.
FT DOMAIN 39..74
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 78..109
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
SQ SEQUENCE 109 AA; 12129 MW; 5C7A0D3D25634A72 CRC64;
MSITDVLSAD DIAAALQECQ DPDTFEPQKF FQTSGLSKMS ASQVKDVFRF IDNDQSGYLD
EEELKFFLQK FESGARELTE SETKSLMAAA DNDGDGKIGA EEFQEMVHS
//
