ID H0X2C8_OTOGA Unreviewed; 359 AA.
AC H0X2C8;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Microfibril associated protein 3 {ECO:0000313|Ensembl:ENSOGAP00000009202.2};
GN Name=MFAP3 {ECO:0000313|Ensembl:ENSOGAP00000009202.2};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000009202.2, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000009202.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAQR03007972; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003782068.1; XM_003782020.2.
DR AlphaFoldDB; H0X2C8; -.
DR STRING; 30611.ENSOGAP00000009202; -.
DR Ensembl; ENSOGAT00000010290.2; ENSOGAP00000009202.2; ENSOGAG00000010287.2.
DR GeneID; 100944559; -.
DR KEGG; oga:100944559; -.
DR CTD; 4238; -.
DR eggNOG; ENOG502QW9J; Eukaryota.
DR GeneTree; ENSGT00390000011576; -.
DR HOGENOM; CLU_056017_0_0_1; -.
DR InParanoid; H0X2C8; -.
DR OMA; KPHCCLF; -.
DR OrthoDB; 3023373at2759; -.
DR TreeFam; TF333205; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR14340; MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 3; 1.
DR PANTHER; PTHR14340:SF4; MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 3; 1.
DR Pfam; PF13927; Ig_3; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00408; IGc2; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005225};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..359
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003544316"
FT TRANSMEM 149..172
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 46..137
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 282..306
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 318..359
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 318..342
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 359 AA; 39892 MW; 2A65D3B5975FD67D CRC64;
MKPHCCLFTL VVSVTVPAAF VFEDVDFNQM APWGENHSSY NASFPPTFEP SPSSHSGDDV
IIAKEGTSVS MECLLTAGHY EDVHWYNSKG QQLDGRSKGG KWLVSDNFLN ITNIAFDDRG
LYTCFITSPT RASYSVTLRV IFTSGDMSVY YMIVCLIAFT ITLILNVTRL CMMSSHLRKT
EKAINEFFRT EGAEKLQKAF EIAKRIPIIT SAKTLELAKV TQFKTMEFAR YIEELARSVP
LPPLILNCRA FVEEMFEAVR VDDPDDIGER IKERPALNAQ SGIFVINPEM GRSNSPGGDS
DDGSLNEQGQ EIAVQVSVHL QSETKSIDTD SQDSSHFSPP DDIGSAESNK DGTYENCQL
//
