ID H0X7D3_OTOGA Unreviewed; 227 AA.
AC H0X7D3;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=BTG anti-proliferation factor 4 {ECO:0000313|Ensembl:ENSOGAP00000011317.2};
GN Name=BTG4 {ECO:0000313|Ensembl:ENSOGAP00000011317.2};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000011317.2, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000011317.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the BTG family. {ECO:0000256|ARBA:ARBA00007989}.
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DR EMBL; AAQR03115801; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H0X7D3; -.
DR STRING; 30611.ENSOGAP00000011317; -.
DR Ensembl; ENSOGAT00000012635.2; ENSOGAP00000011317.2; ENSOGAG00000012632.2.
DR eggNOG; KOG4006; Eukaryota.
DR GeneTree; ENSGT00950000182952; -.
DR HOGENOM; CLU_079660_3_0_1; -.
DR InParanoid; H0X7D3; -.
DR OMA; YLHRKTY; -.
DR TreeFam; TF105272; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0003730; F:mRNA 3'-UTR binding; IEA:Ensembl.
DR GO; GO:0160021; P:maternal-to-zygotic transition of gene expression; IEA:Ensembl.
DR GO; GO:0045930; P:negative regulation of mitotic cell cycle; IEA:Ensembl.
DR Gene3D; 3.90.640.90; Anti-proliferative protein, N-terminal domain; 1.
DR InterPro; IPR002087; Anti_prolifrtn.
DR InterPro; IPR033332; BTG.
DR InterPro; IPR036054; BTG-like_sf.
DR PANTHER; PTHR22978; B-CELL TRANSLOCATION GENE; 1.
DR PANTHER; PTHR22978:SF5; PROTEIN BTG4; 1.
DR Pfam; PF07742; BTG; 1.
DR PRINTS; PR00310; ANTIPRLFBTG1.
DR SMART; SM00099; btg1; 1.
DR SUPFAM; SSF160696; BTG domain-like; 1.
DR PROSITE; PS00960; BTG_1; 1.
DR PROSITE; PS01203; BTG_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000005225}.
FT DOMAIN 42..62
FT /note="Anti-proliferative protein"
FT /evidence="ECO:0000259|PROSITE:PS00960"
FT DOMAIN 88..107
FT /note="Anti-proliferative protein"
FT /evidence="ECO:0000259|PROSITE:PS01203"
SQ SEQUENCE 227 AA; 26359 MW; 1700DAA7AC64A615 CRC64;
CFSSMVSSVF FVTRLVKKHD KLNKQQIEDF AEKLMTILFE TYRSHWHSDC PSKGQGFRCI
RINNYQNKDP ILEKACAESN VDFSQLGLPK EMTIWIDPFE VCCRYGEKNH PFTIASFRGR
CEEWELYRQI SHAVNRASVD YSSATSSDEE SCSKELRIIP KVSNPKSIYQ VENLKHPFQS
WFQISRKKNV ADGRVGLLGS TFQAVHKQPK CHRTAVGRVD RYHWVNA
//
