ID H0X7U2_OTOGA Unreviewed; 158 AA.
AC H0X7U2;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=Kv channel-interacting protein 4 {ECO:0000256|ARBA:ARBA00040738};
GN Name=KCNIP4 {ECO:0000313|Ensembl:ENSOGAP00000011505.2};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000011505.2, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000011505.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004202};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004202}.
CC -!- SIMILARITY: Belongs to the recoverin family.
CC {ECO:0000256|ARBA:ARBA00006049}.
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DR EMBL; AAQR03102846; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03102847; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03102848; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03102849; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03102850; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03102851; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03102852; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03102853; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03102854; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H0X7U2; -.
DR STRING; 30611.ENSOGAP00000011505; -.
DR Ensembl; ENSOGAT00000012840.2; ENSOGAP00000011505.2; ENSOGAG00000012838.2.
DR eggNOG; KOG0044; Eukaryota.
DR GeneTree; ENSGT00940000158985; -.
DR HOGENOM; CLU_072366_5_0_1; -.
DR InParanoid; H0X7U2; -.
DR OMA; PRPLDPX; -.
DR TreeFam; TF318560; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0005777; C:peroxisome; IEA:Ensembl.
DR GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:Ensembl.
DR GO; GO:0005509; F:calcium ion binding; IEA:Ensembl.
DR GO; GO:0015459; F:potassium channel regulator activity; IEA:Ensembl.
DR GO; GO:1901379; P:regulation of potassium ion transmembrane transport; IEA:Ensembl.
DR CDD; cd00051; EFh; 2.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR028846; Recoverin.
DR PANTHER; PTHR23055; CALCIUM BINDING PROTEINS; 1.
DR PANTHER; PTHR23055:SF30; KV CHANNEL-INTERACTING PROTEIN 4; 1.
DR Pfam; PF13499; EF-hand_7; 1.
DR Pfam; PF13833; EF-hand_8; 1.
DR PRINTS; PR00450; RECOVERIN.
DR SMART; SM00054; EFh; 2.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS00018; EF_HAND_1; 2.
DR PROSITE; PS50222; EF_HAND_2; 2.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000005225};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 27..62
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 63..98
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
SQ SEQUENCE 158 AA; 18373 MW; 35682017C513B8B0 CRC64;
FPQECPSGVV NEETFKEIYS QFFPQGDSTT YAHFLFNAFD TDHNGAVSFE DFIKGLSILL
RGTVQEKLNW AFNLYDINKD GYITKEEMLD IMKAIYDMMG KCTYPVLKED APRQHVETFF
QKMDRTMLGV IPISPFQDEN IMRSMQLFEN IAELYTEA
//
