ID H0XDF5_OTOGA Unreviewed; 341 AA.
AC H0XDF5;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Fibronectin type III and ankyrin repeat domains 1 {ECO:0000313|Ensembl:ENSOGAP00000013898.2};
GN Name=FANK1 {ECO:0000313|Ensembl:ENSOGAP00000013898.2};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000013898.2, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000013898.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAQR03106846; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H0XDF5; -.
DR STRING; 30611.ENSOGAP00000013898; -.
DR Ensembl; ENSOGAT00000015525.2; ENSOGAP00000013898.2; ENSOGAG00000015521.2.
DR eggNOG; KOG0504; Eukaryota.
DR GeneTree; ENSGT00940000160878; -.
DR HOGENOM; CLU_000134_5_0_1; -.
DR InParanoid; H0XDF5; -.
DR OMA; NFGHRLR; -.
DR TreeFam; TF106234; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0000785; C:chromatin; IEA:Ensembl.
DR GO; GO:0036064; C:ciliary basal body; IEA:Ensembl.
DR GO; GO:0097546; C:ciliary base; IEA:Ensembl.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:Ensembl.
DR CDD; cd00063; FN3; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR24183; FIBRONECTIN TYPE 3 AND ANKYRIN REPEAT DOMAINS PROTEIN 1; 1.
DR PANTHER; PTHR24183:SF1; FIBRONECTIN TYPE 3 AND ANKYRIN REPEAT DOMAINS PROTEIN 1; 1.
DR Pfam; PF12796; Ank_2; 2.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 6.
DR SMART; SM00060; FN3; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 4.
DR PROSITE; PS50088; ANK_REPEAT; 5.
DR PROSITE; PS50853; FN3; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Reference proteome {ECO:0000313|Proteomes:UP000005225};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 7..104
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REPEAT 139..171
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 172..204
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 205..237
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 239..272
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 273..305
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
SQ SEQUENCE 341 AA; 37950 MW; FA899BB3DA3D455E CRC64;
EIPPLSKPHP PVVGKVTHHS IELYWDLDKR AKRQGPQEQW FRFSIEEEDP KLHTYGIIYT
GYSSKHVIEG LEPRTLYKFR LKVTSPSGEF EYSPVISVST TREPMSSEHF HRAVSVNDED
LLVRILQGGH INIDVPNKFG FTALMVAAQK GYTRLVEILV SNGADVNLRN GSGKDSLMLA
CYAGHLDVVR YLRRHGASWE TRDLGGCTAM HWAIDGGHCH VIEWMIKDGC AVDVVDTGSG
WTPLMRLSAV SGNQGVASLL IEAGANVNVK DRDGKTPLMV AVLNNYEELV QILLDKGADA
SVKNEFGKGV LEMARVFDRQ NVISLLEERK NASFYLNTCV C
//
