ID H0XDH2_OTOGA Unreviewed; 257 AA.
AC H0XDH2;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Zinc finger AN1-type containing 2B {ECO:0000313|Ensembl:ENSOGAP00000013918.2};
GN Name=ZFAND2B {ECO:0000313|Ensembl:ENSOGAP00000013918.2};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000013918.2, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000013918.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AAQR03031245; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_012657642.1; XM_012802188.1.
DR AlphaFoldDB; H0XDH2; -.
DR STRING; 30611.ENSOGAP00000013918; -.
DR Ensembl; ENSOGAT00000015546.2; ENSOGAP00000013918.2; ENSOGAG00000015541.2.
DR GeneID; 100944368; -.
DR CTD; 130617; -.
DR eggNOG; KOG3183; Eukaryota.
DR GeneTree; ENSGT00940000159648; -.
DR HOGENOM; CLU_061621_2_0_1; -.
DR InParanoid; H0XDH2; -.
DR OMA; DESKHNR; -.
DR OrthoDB; 103213at2759; -.
DR TreeFam; TF314219; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:Ensembl.
DR GO; GO:0016020; C:membrane; IEA:Ensembl.
DR GO; GO:0000502; C:proteasome complex; IEA:Ensembl.
DR GO; GO:0036435; F:K48-linked polyubiquitin modification-dependent protein binding; IEA:Ensembl.
DR GO; GO:0043130; F:ubiquitin binding; IEA:Ensembl.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR GO; GO:0043567; P:regulation of insulin-like growth factor receptor signaling pathway; IEA:Ensembl.
DR GO; GO:0006616; P:SRP-dependent cotranslational protein targeting to membrane, translocation; IEA:Ensembl.
DR Gene3D; 4.10.1110.10; AN1-like Zinc finger; 2.
DR InterPro; IPR035896; AN1-like_Znf.
DR InterPro; IPR003903; UIM_dom.
DR InterPro; IPR000058; Znf_AN1.
DR PANTHER; PTHR14677:SF13; AN1-TYPE ZINC FINGER PROTEIN 2B; 1.
DR PANTHER; PTHR14677; ARSENITE INDUCUBLE RNA ASSOCIATED PROTEIN AIP-1-RELATED; 1.
DR Pfam; PF02809; UIM; 2.
DR Pfam; PF01428; zf-AN1; 2.
DR SMART; SM00726; UIM; 2.
DR SMART; SM00154; ZnF_AN1; 2.
DR SUPFAM; SSF118310; AN1-like Zinc finger; 2.
DR PROSITE; PS50330; UIM; 2.
DR PROSITE; PS51039; ZF_AN1; 2.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000005225};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00449}.
FT DOMAIN 4..52
FT /note="AN1-type"
FT /evidence="ECO:0000259|PROSITE:PS51039"
FT DOMAIN 94..142
FT /note="AN1-type"
FT /evidence="ECO:0000259|PROSITE:PS51039"
FT REGION 153..187
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 257 AA; 27914 MW; 38A4B81265D9C8E1 CRC64;
MEFPDLGAHC SEPSCQRLDF LPLKCDACSG IFCADHVAYA QHHCGSAYQK DIQVPVCPLC
NVPVPVARGE PPDRAVGEHI DRDCRSDPAQ QKRKIFTNKC ERSGCRQREM MKLTCDRCGR
NFCIKHRHPL DHDCSGEGHP TSQAGLAAIS RAKGLASTST IPSPSRTLPS CTSPSRATTQ
SPSRTAPPVI ALQNGLSEDE ALQRALEMSL AETKPQVPSS QEEEDLALAQ ALSASEAEYQ
QQQAQSRSLK PSNCSLC
//
