ID H0XE88_OTOGA Unreviewed; 340 AA.
AC H0XE88;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Clusterin associated protein 1 {ECO:0000313|Ensembl:ENSOGAP00000014247.2};
GN Name=CLUAP1 {ECO:0000313|Ensembl:ENSOGAP00000014247.2};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000014247.2, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000014247.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the CLUAP1 family.
CC {ECO:0000256|ARBA:ARBA00008340}.
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DR EMBL; AAQR03078259; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03078260; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03078261; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H0XE88; -.
DR STRING; 30611.ENSOGAP00000014247; -.
DR Ensembl; ENSOGAT00000015910.2; ENSOGAP00000014247.2; ENSOGAG00000015905.2.
DR eggNOG; KOG3647; Eukaryota.
DR GeneTree; ENSGT00390000008957; -.
DR HOGENOM; CLU_034981_1_0_1; -.
DR InParanoid; H0XE88; -.
DR OMA; ERFEXND; -.
DR TreeFam; TF314639; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR GO; GO:0097546; C:ciliary base; IEA:Ensembl.
DR GO; GO:0097542; C:ciliary tip; IEA:Ensembl.
DR GO; GO:0030991; C:intraciliary transport particle A; IEA:Ensembl.
DR GO; GO:0030992; C:intraciliary transport particle B; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0035082; P:axoneme assembly; IEA:Ensembl.
DR GO; GO:0021508; P:floor plate formation; IEA:Ensembl.
DR GO; GO:0001947; P:heart looping; IEA:Ensembl.
DR GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR GO; GO:0007224; P:smoothened signaling pathway; IEA:Ensembl.
DR InterPro; IPR019366; Clusterin-associated_protein-1.
DR PANTHER; PTHR21547; CLUSTERIN ASSOCIATED PROTEIN 1; 1.
DR PANTHER; PTHR21547:SF0; CLUSTERIN-ASSOCIATED PROTEIN 1; 1.
DR Pfam; PF10234; Cluap1; 1.
PE 3: Inferred from homology;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium biogenesis/degradation {ECO:0000256|ARBA:ARBA00022794};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000005225}.
FT REGION 231..340
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 137..231
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 286..314
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 324..340
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 340 AA; 39282 MW; 12B0C72548F21523 CRC64;
ATKAHIKLNT KKLYQADGYA VKELLKITSV LYNAMKTKGM EGSQIGEEDI SKFKFDLGSK
IADLKAARQL ASEITSKGAS LYDLLGKEVE LREMRTEAIG RPLEINETEK VIRIAIKEIL
TQVQKTKDLL NNVASDEANL EAKIEKRKLE LERNRKRLQT LQSVRPAFMD EYEKIEEELQ
KQYDIYLEKF RNLTYLEQQL EDHHRMEQER FEEAENTLRL MQNKLKEEEK RLLKSGSNDG
SDIEIQEDDE SDSELEERRL SKPRTAMEVL MQGRPSKRVV GTMQGGDSDD EDDSEDSEID
MEDDEEDDDD LEDESIALSP AKPSRRVRKP EPLDESDNDF
//
