ID H0XFR9_OTOGA Unreviewed; 259 AA.
AC H0XFR9;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=Haloacid dehalogenase-like hydrolase domain-containing protein 2 {ECO:0000256|ARBA:ARBA00039666};
GN Name=HDHD2 {ECO:0000313|Ensembl:ENSOGAP00000014874.2};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000014874.2, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000014874.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the HAD-like hydrolase superfamily.
CC {ECO:0000256|ARBA:ARBA00007958}.
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DR EMBL; AAQR03027458; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03027459; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03027460; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03027461; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03027462; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03027463; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03027464; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03027465; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003784767.1; XM_003784719.2.
DR AlphaFoldDB; H0XFR9; -.
DR STRING; 30611.ENSOGAP00000014874; -.
DR Ensembl; ENSOGAT00000016622.2; ENSOGAP00000014874.2; ENSOGAG00000016619.2.
DR GeneID; 100961599; -.
DR CTD; 84064; -.
DR eggNOG; KOG3040; Eukaryota.
DR GeneTree; ENSGT00940000155805; -.
DR HOGENOM; CLU_043473_4_0_1; -.
DR InParanoid; H0XFR9; -.
DR OMA; PNPYFFE; -.
DR OrthoDB; 2876640at2759; -.
DR TreeFam; TF314344; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0019899; F:enzyme binding; IEA:Ensembl.
DR GO; GO:0016791; F:phosphatase activity; IEA:InterPro.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR CDD; cd07509; HAD_PPase; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 2.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR006357; HAD-SF_hydro_IIA.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR006355; LHPP/HDHD2.
DR NCBIfam; TIGR01460; HAD-SF-IIA; 1.
DR NCBIfam; TIGR01458; HAD-SF-IIA-hyp3; 1.
DR PANTHER; PTHR19288; 4-NITROPHENYLPHOSPHATASE-RELATED; 1.
DR PANTHER; PTHR19288:SF46; HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING PROTEIN 2; 1.
DR Pfam; PF13344; Hydrolase_6; 1.
DR Pfam; PF13242; Hydrolase_like; 1.
DR SFLD; SFLDG01139; C2.A:_Pyridoxal_Phosphate_Phos; 1.
DR SFLD; SFLDS00003; Haloacid_Dehalogenase; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000005225}.
SQ SEQUENCE 259 AA; 28569 MW; EF90AC616D7FB15A CRC64;
MAARRALKAV LVDLNGTLHI EDAAVPGSQE ALKRLRSTSV MVRFVTNTTK ESKQDLLERL
KKLEFDISED EIFTSLTAAR SLVEQKQVRP MLLVDDRALP DFKGIETSDP NAVVIGLAPE
HFHYQTLNQA FRLLLDGAPL IAIHKARYYK RKDGLALGPG PFVTALEYAT DTKATVVGKP
EKTFFLEALR GTGCEPEEAV MIGDDCRDDV GGAQNAGMRG ILVKTGKYRA ADEEKINPAP
YLTCESFPHA VDHILQHLL
//
