ID   H0XH01_OTOGA            Unreviewed;      1640 AA.
AC   H0XH01;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   27-MAR-2024, entry version 60.
DE   SubName: Full=Maestro heat like repeat family member 1 {ECO:0000313|Ensembl:ENSOGAP00000015382.2};
GN   Name=MROH1 {ECO:0000313|Ensembl:ENSOGAP00000015382.2};
OS   Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC   Galagidae; Otolemur.
OX   NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000015382.2, ECO:0000313|Proteomes:UP000005225};
RN   [1] {ECO:0000313|Proteomes:UP000005225}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   The Broad Institute Genome Sequencing Platform;
RA   Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA   Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA   Walker B.J., Sharpe T., Hall G.;
RT   "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL   Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSOGAP00000015382.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AAQR03179275; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03179276; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03179277; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03179278; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03179279; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03179280; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03179281; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSOGAT00000017177.2; ENSOGAP00000015382.2; ENSOGAG00000017172.2.
DR   eggNOG; KOG2032; Eukaryota.
DR   GeneTree; ENSGT00940000156930; -.
DR   HOGENOM; CLU_003168_0_1_1; -.
DR   InParanoid; H0XH01; -.
DR   OMA; EVYIKAM; -.
DR   TreeFam; TF315201; -.
DR   Proteomes; UP000005225; Unassembled WGS sequence.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 4.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR000357; HEAT.
DR   InterPro; IPR021133; HEAT_type_2.
DR   InterPro; IPR045206; Maestro_heat-like_prot.
DR   InterPro; IPR048465; Maestro_HEAT_rpt.
DR   PANTHER; PTHR23120:SF44; MAESTRO HEAT-LIKE REPEAT-CONTAINING PROTEIN FAMILY MEMBER 1; 1.
DR   PANTHER; PTHR23120; MAESTRO-RELATED HEAT DOMAIN-CONTAINING; 1.
DR   Pfam; PF02985; HEAT; 1.
DR   Pfam; PF21047; Maestro_HEAT; 1.
DR   SUPFAM; SSF48371; ARM repeat; 2.
DR   PROSITE; PS50077; HEAT_REPEAT; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000005225};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   REPEAT          1610..1640
FT                   /note="HEAT"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
SQ   SEQUENCE   1640 AA;  180862 MW;  6C323672FDD54539 CRC64;
     MTESYVKRLS CALLGAITDK DPEVQEQVCS ALCSIGEAQP EETLRACEEH LRQQSKLAHP
     YRALVLRAME MVLSRHTGKL DKDTANIVIH LASSEMTKTK ELVCGWQQAA SSVLVAVGRQ
     FINRVMEELL SKFQPGVLPH CSVVQTLANL AVSNVFGMVP FLPSILSTML PMLGMAKQDE
     MRVTFCSALQ SFSESALEYL ANLDQAPDPT VRKDTFAADI FSAYDILFNH WLQSREAKLR
     LAVVEALGPM SLLLPSERLE EQLPKLLPGV LALYKKHAET FYVSKSLGQI LEAAVSVSSR
     TLEGQLDALL TALHAQQICV PVESLSPLVM SNQKEVLRCF TVLARSAPGR LLAFLLPKLD
     TSNERLRVGT LQVLKHVINS AAAQMEAQKP FILSSMRLPL LDPNPQVKRA VVQVISAMAH
     HGYLEQPGGE VMVEYLVQQC ALPPEQEPEN LGPNSEDLMA DSVRAMSIRT LYLVSTAMDR
     MSDVLWPYLL EFLIPVRFTR ALTPLCRSLL HLAQKRQEVG ADAFLIQQGA HVRLPSPYAV
     ATRLLVVSSS PYLGGGRGVA SLRLLNALHR SVHPLLGQQW ETAIPLLLEY LEEYTEETLP
     QKEWEEKLLL FLRDTLAVVS DNLWVCQLSL EMCRQLPCYN GTPQEKHFLY KCIGTTLGVA
     SSKDVVRKHL QELLETARYQ EQADREGLAC CFGICASSHL EDVLAQLEDF VRSAVFRKPI
     GIFNIFKDRS ENEVEKVKSG LILCYGHVAT QAPREGMLAR VESDILPGMF RCFSTKVLGI
     KVETKDPALK LCLVRSSCMV SHAICSAQAS SFHFSRKAEL VAQMMELIRA EPVDTLRTPI
     RKEAMLTCAH LASLEPVLGE QAQADVIQGC LHSVMALVPE PQGEHQGCEE VLYLDTMCAL
     KDLMTSLLQR DVTPQGLQVM VEHLSPWIKS PQGHERVQAL SLSGCLLQYF RERLHVSALT
     PFHNLGLLVG LFSPRCADPW PAARQEAIGC VHALLSLQLC YEGFSRDYCD DSTKRLLALK
     DGLAHPDPAI MLHTCHIMAQ VIAKRLPPDQ LISLLLTMFE GLEDPDKNCS QATSAMINCL
     LQARGSALLE KVPELVSVLR SKLQAAPEHI LPAAQHSVYL LASQHCAAVV SSLLGSPLPF
     DSHTCLLWRA LAVEPSLATQ VLRLLLERVS RDVPFKENRT FLLGSTPDRV ATLLPLSATC
     ALHEVVSAPA SGPAVLELYP QLFVALLLRV SCMLGVQLPR NLEAKERRAT SLPTATRSLE
     PCSCAVDALQ AVLLRGGSEG VVQGVELEGG WELLRTSSGH EEGTTRLATA MAKCAGPRLP
     LVTKALICTQ NSPYEIQRIT STAFLAELLS SNVVNDLMLL ESLLDSLVAR QKDPCTSVRR
     LVLRGLANLA SGSPEKVRAR GPQLLTAMIG GLDDGDDLHS LVALEAMAGL MRLLPLVEPR
     DLHPVLLHIT IRVRPFFDSE KTEVRTASIC LFGHLNEACH GDCEDVFLEQ VVSGLVPLLL
     HLQDPQTPVA SACKFALCMS SPNLECEELS GTFQRHLQDG RGLHYGEFLN ATCKHLMLHF
     PDLLGRLVRD SLFYFKSGWE DIRAAAPLFT GFLVLHAESR HWSQVDLEQL LMALQLLLRD
     PAPLVRVKAA EALGRLVKFA
//