GenomeNet

Database: UniProt
Entry: H0XH28_OTOGA
LinkDB: H0XH28_OTOGA
Original site: H0XH28_OTOGA 
ID   H0XH28_OTOGA            Unreviewed;       883 AA.
AC   H0XH28;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   25-APR-2018, entry version 38.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSOGAP00000015414};
GN   Name=NDST2 {ECO:0000313|Ensembl:ENSOGAP00000015414};
OS   Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini;
OC   Lorisiformes; Galagidae; Otolemur.
OX   NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000015414};
RN   [1] {ECO:0000313|Ensembl:ENSOGAP00000015414}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   The Broad Institute Genome Sequencing Platform;
RA   Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA   Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA   Walker B.J., Sharpe T., Hall G.;
RT   "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL   Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSOGAP00000015414}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JAN-2012) to UniProtKB.
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DR   EMBL; AAQR03018791; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_003783598.1; XM_003783550.1.
DR   RefSeq; XP_012656822.1; XM_012801368.1.
DR   STRING; 30611.ENSOGAP00000015414; -.
DR   Ensembl; ENSOGAT00000017212; ENSOGAP00000015414; ENSOGAG00000017207.
DR   GeneID; 100943609; -.
DR   CTD; 8509; -.
DR   eggNOG; KOG3703; Eukaryota.
DR   eggNOG; ENOG410XQN4; LUCA.
DR   GeneTree; ENSGT00760000119023; -.
DR   InParanoid; H0XH28; -.
DR   OMA; NYYRGLD; -.
DR   OrthoDB; EOG091G02CP; -.
DR   TreeFam; TF313193; -.
DR   Proteomes; UP000005225; Unassembled WGS sequence.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:Ensembl.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015016; F:[heparan sulfate]-glucosamine N-sulfotransferase activity; IEA:InterPro.
DR   GO; GO:0019213; F:deacetylase activity; IEA:Ensembl.
DR   GO; GO:0015012; P:heparan sulfate proteoglycan biosynthetic process; IEA:Ensembl.
DR   GO; GO:0002002; P:regulation of angiotensin levels in blood; IEA:Ensembl.
DR   InterPro; IPR021930; Heparan_SO4_deacetylase.
DR   InterPro; IPR037359; NST/OST.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000863; Sulfotransferase_dom.
DR   PANTHER; PTHR10605; PTHR10605; 1.
DR   Pfam; PF12062; HSNSD; 1.
DR   Pfam; PF00685; Sulfotransfer_1; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005225};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005225};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     20     38       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       27    514       HSNSD. {ECO:0000259|Pfam:PF12062}.
FT   DOMAIN      604    852       Sulfotransfer_1. {ECO:0000259|Pfam:
FT                                PF00685}.
SQ   SEQUENCE   883 AA;  100928 MW;  52E9DC91BBF6F764 CRC64;
     MLQLWKVVRP ARQLELHRLI LLLIAFSLGS MGFLAYYVST SPKAKEPLPL PLGDCSSGGA
     VGPGPARPPV PPRPPRPPET ARTEPVVLVF VESAYSQLGQ EIVAILESSR FRYSTELAPG
     RGDMPTLTDH TRGRYVLVIY ENLLKYVNLD AWSRELLDRY CVEYGVGIIG FFRAHEHSLL
     SAQLKGFPLF LHSNLGLRDY QVNPSAPLLH LTRPSHLEPG PLPGDDWTIF QSNHSTYEPV
     LLASLRPAEL PVPGPVPRRA RLPTVVQDLG LHDGIQRVLF GHGLSFWLHK LIFVDAVAYL
     TGKRLCLDLD RYILVDIDDI FVGKEGTRMK VADVEALLTT QNKLRTLVPN FTFNLGFSGK
     FYHTGTEEED AGDDMLLKHR QEFWWFPHMW SHMQPHLFHN RSVLADQMRL NKQFALEHGI
     PTDLGYAVAP HHSGVYPIHT QLYEAWKSVW GIQVTSTEEY PHLRPARYRR GFIHNGIMVL
     PRQTCGLFTH TIFYNEYPGG SHELDRSIRG GELFLTVLLN PISIFMTHLS NYGNDRLGLY
     TFESLVRFLQ CWTRLRLQTL PPVPLAQKYF ELFPQERSPL WQNPCDDKRH KDIWSKEKTC
     DRLPKFLIVG PQKTGTTAIH FFLNLHPAVT SSFPSPSTFE EIQFFSGPNY HKGIDWYMDF
     FPVPSNASTD FLFEKSATYF DSEVVPRRGA ALLPRAKIIT VLTNPADRAY SWYQHQRAHG
     DPVALNYTFY QVISASSQAP LALRSLQNRC LIPGYYSTHL QRWLTYYPSG QLLIVDGQEL
     RTNPAASMEN IQKFLGITPF LNYTRTLRFD EDKGFWCQGL EGGKTRCLGR SKGRRYPDMD
     TESRLFLTDF FRNHNLELSK LLSRLGQPVP SWLREELQHS SLG
//
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