ID H0XMQ1_OTOGA Unreviewed; 368 AA.
AC H0XMQ1;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=IBB domain-containing protein {ECO:0000259|PROSITE:PS51214};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000017392.1, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000017392.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the importin alpha family.
CC {ECO:0000256|ARBA:ARBA00010394}.
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DR EMBL; AAQR03012036; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H0XMQ1; -.
DR STRING; 30611.ENSOGAP00000017392; -.
DR Ensembl; ENSOGAT00000033797.1; ENSOGAP00000017392.1; ENSOGAG00000028256.1.
DR eggNOG; KOG0166; Eukaryota.
DR GeneTree; ENSGT01050000244891; -.
DR HOGENOM; CLU_018084_6_1_1; -.
DR InParanoid; H0XMQ1; -.
DR OMA; VNICPDE; -.
DR TreeFam; TF101178; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0061608; F:nuclear import signal receptor activity; IEA:InterPro.
DR GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR Gene3D; 1.20.5.690; Importin-alpha, importin-beta-binding domain; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR002652; Importin-a_IBB.
DR InterPro; IPR036975; Importin-a_IBB_sf.
DR PANTHER; PTHR23316; IMPORTIN ALPHA; 1.
DR PANTHER; PTHR23316:SF12; IMPORTIN SUBUNIT ALPHA-1; 1.
DR Pfam; PF00514; Arm; 4.
DR Pfam; PF01749; IBB; 1.
DR SMART; SM00185; ARM; 5.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50176; ARM_REPEAT; 3.
DR PROSITE; PS51214; IBB; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000005225};
KW Transport {ECO:0000256|PROSITE-ProRule:PRU00561}.
FT DOMAIN 1..57
FT /note="IBB"
FT /evidence="ECO:0000259|PROSITE:PS51214"
FT REPEAT 155..182
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 234..276
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 276..318
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 368 AA; 39948 MW; 705E0D47212C3495 CRC64;
NENANSPAAQ LNRFKNKGKD STEMRRRQIE VNVELRKAKN DDQMLKRRNV SSFPDDATFP
LQENQNIQGT INWSVDNIVK GINSTNMENQ LQATQAARKL LSREKQPPID SGLISEFVSF
LGRTDCSPIQ FESALALINI ASGTSEQTKA VVDGGAIPAF ISLLASPHAI SEQAVWALGN
IAGDGSVFFD PLLALLAIPD MSSLSCGYLR NLPWTLSNLC RNKNPAPPLD AVEQILPTLV
RLLQHDDPEV LADTCWAISY LTDGPNEQIE MVVKTGVVPQ LVKLLGATEL PIVTPALKAI
GNIVTGTDEQ TQVVIDAGAL TVFPSLLTNQ TNIQKEATWT MSNITAGRQD QIQQVVNHGL
VPLLVGVL
//
