ID H0XMR9_OTOGA Unreviewed; 90 AA.
AC H0XMR9;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=Non-histone chromosomal protein HMG-17 {ECO:0000256|ARBA:ARBA00040304};
DE AltName: Full=High mobility group nucleosome-binding domain-containing protein 2 {ECO:0000256|ARBA:ARBA00042290};
GN Name=LOC100966179 {ECO:0000313|Ensembl:ENSOGAP00000017410.1};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000017410.1, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000017410.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Binds to the inner side of the nucleosomal DNA thus altering
CC the interaction between the DNA and the histone octamer. May be
CC involved in the process which maintains transcribable genes in a unique
CC chromatin conformation. {ECO:0000256|ARBA:ARBA00037490}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the HMGN family.
CC {ECO:0000256|ARBA:ARBA00007696}.
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DR EMBL; AAQR03000695; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_012658705.1; XM_012803251.1.
DR AlphaFoldDB; H0XMR9; -.
DR STRING; 30611.ENSOGAP00000017410; -.
DR Ensembl; ENSOGAT00000031330.1; ENSOGAP00000017410.1; ENSOGAG00000026562.1.
DR GeneID; 100966179; -.
DR KEGG; oga:100966179; -.
DR eggNOG; ENOG502S5FK; Eukaryota.
DR GeneTree; ENSGT00950000182802; -.
DR HOGENOM; CLU_141985_0_2_1; -.
DR InParanoid; H0XMR9; -.
DR OMA; DAKWSCV; -.
DR OrthoDB; 2879721at2759; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0000785; C:chromatin; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0031492; F:nucleosomal DNA binding; IEA:InterPro.
DR InterPro; IPR000079; HMGN_fam.
DR PANTHER; PTHR23087:SF13; NON-HISTONE CHROMOSOMAL PROTEIN HMG-17; 1.
DR PANTHER; PTHR23087; NONHISTONE CHROMOSOMAL PROTEIN HMG; 1.
DR Pfam; PF01101; HMG14_17; 1.
DR PRINTS; PR00925; NONHISHMG17.
DR SMART; SM00527; HMG17; 1.
DR PROSITE; PS00355; HMG14_17; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000005225}.
FT REGION 1..90
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..26
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 90 AA; 9395 MW; B1D717CC73C9A9C8 CRC64;
MPKRKAEGDA KGDKAKAKDE PQRRSARLSA KPAPPKPEPK PKKAPAKKGE KVPKGKKGKA
DASKEGNNPA ENGDAKTDQA QKAEGAGDAK
//
