ID   H0XNK2_OTOGA            Unreviewed;       490 AA.
AC   H0XNK2;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   27-MAR-2024, entry version 51.
DE   SubName: Full=DEP domain containing 4 {ECO:0000313|Ensembl:ENSOGAP00000017693.1};
GN   Name=DEPDC4 {ECO:0000313|Ensembl:ENSOGAP00000017693.1};
OS   Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC   Galagidae; Otolemur.
OX   NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000017693.1, ECO:0000313|Proteomes:UP000005225};
RN   [1] {ECO:0000313|Proteomes:UP000005225}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   The Broad Institute Genome Sequencing Platform;
RA   Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA   Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA   Walker B.J., Sharpe T., Hall G.;
RT   "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL   Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSOGAP00000017693.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AAQR03016671; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; H0XNK2; -.
DR   STRING; 30611.ENSOGAP00000017693; -.
DR   Ensembl; ENSOGAT00000029082.1; ENSOGAP00000017693.1; ENSOGAG00000026205.1.
DR   eggNOG; ENOG502QW4D; Eukaryota.
DR   GeneTree; ENSGT00950000182976; -.
DR   HOGENOM; CLU_033776_1_0_1; -.
DR   InParanoid; H0XNK2; -.
DR   OMA; LMQNVVF; -.
DR   TreeFam; TF328365; -.
DR   Proteomes; UP000005225; Unassembled WGS sequence.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd04446; DEP_DEPDC4; 1.
DR   CDD; cd04405; RhoGAP_BRCC3-like; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR000591; DEP_dom.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR16206; DEP DOMAIN-CONTAINING; 1.
DR   PANTHER; PTHR16206:SF10; DEP DOMAIN-CONTAINING PROTEIN 4; 1.
DR   Pfam; PF00610; DEP; 1.
DR   SMART; SM00049; DEP; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50186; DEP; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000005225}.
FT   DOMAIN          14..104
FT                   /note="DEP"
FT                   /evidence="ECO:0000259|PROSITE:PS50186"
SQ   SEQUENCE   490 AA;  56939 MW;  0EB682112801B3A1 CRC64;
     FQATQLWDGI VHSLHTHVEI KRRRHRLRTY KDCFTGSDAV DVVLSHLMQS TCLSSKDISR
     LKGVRLCQVL MNHKVFEPVG AKLFKTEKEL EFEDSNSSLY RFLDNESSYV FCKRKKDTEN
     GFINETKPEE SLRPEDEMIS NPLAQETSEK RIEEFIHMPS GNPALPPNTT VNKPNLQLSK
     EATEAVWKQQ TLLRIFQLID LPFLENILEP QVKTQNLQLS KEEDLVISNT CLDREVIPSL
     CLPEIDDWLN AAIECLEYFP DQLIVTVSQE LVQNRNEETR SDIQKKILFN VIVKYYHQER
     NCLLTDEYSD IHAAVIELLE NEKTTEALEA IQLYLRLLLP NVREELRRLL TFMAVASQPD
     AYKLQKQYDN KTVVLKTLAK AVLQTKLLLK VQAEQLAWFL LEHHTELFKT PVTLLDLVGK
     KLKKLLHGED PDAISDFTFC QPLTHKEFEK QKGRTIQYLH QLALEINSNP SLSLKQKKKL
     IKEFQKHHPE
//